Results 61 to 70 of about 17,957,914 (306)

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Steady-state analysis toolkit

open access: yes, 2018
Code to run the steady-state trial identification and ...
Daniel Blustein (6157745)   +7 more
core   +1 more source

SSCAR-Steady State Cycle AnalyseR

open access: yes, 2017
This report describes the Steady-State Cycle AnalyseR (SCCAR), a solution engine that enables the steady state evaluation of thermodynamical cycles. SCCAR can be used to parametrically define thermodynamic cycles using a library of predefined building ...
Jahn, Ingo
core   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Stabilization of Sand with Colloidal Nano-Silica Hydrosols

open access: yesApplied Sciences, 2020
Colloidal nano-silica (NS) hydrosols are electrochemically stabilized, polymerized amorphous silica in low viscosity solutions, and in the form of hydrated gels, silica globules or pellicles.
Soheil Ghadr   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

davidhindle/steady-nl-heat: steady-nl-heat

open access: yes, 2023
Steady state, non-linear, heat equation for whole lithosphere temperature/geotherm ...
davidhindle
core   +1 more source

Simulating a Steady-state Heliosphere

open access: yesThe Astrophysical Journal Supplement Series
Ever since the discovery of the solar wind, it has been understood that our solar system resides within a bubble of solar wind plasma that originates from the Sun.
Jacob Heerikhuisen   +2 more
doaj   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Magnetization transfer imaging using steady-state free precession MR sequences [PDF]

open access: yes, 2010
Magnetic resonance imaging (MRI) benefits from an exceptional soft tissue contrast and is therefore an important tool for medical diagnosis. While contrast in conventional MRI is generated by protons with free mobility, magnetization transfer (MT ...
Gloor, Monika
core   +1 more source

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