Results 71 to 80 of about 10,665,013 (352)

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Membrane separation study for methane-hydrogen gas mixtures by molecular simulations

open access: yesCondensed Matter Physics, 2017
Direct simulation results for stationary gas transport through pure silica zeolite membranes (MFI, LTA and DDR types) are presented using a hybrid, non-equilibrium molecular dynamics simulation methodology introduced recently.
T. Kovács, S. Papp, T. Kristóf
doaj   +1 more source

Fault Location in Power Electrical Traction Line System

open access: yesEnergies, 2012
In this paper, methods of fault location are discussed in electrical traction single-end direct power supply network systems. Based on the distributed parameter model of the system, the position of the short-circuit fault can be located with the aid of ...
Yimin Zhou, Guoqing Xu, Yanfeng Chen
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Steady-state eternal inflation

open access: yesPhysical Review D, 2002
Since the advent of inflation, several theorems have been proven suggesting that although inflation can (and generically does) continue eternally into the future, it cannot be extended eternally into the past to create a ``steady-state'' model with no initial time.
Aguirre, Anthony, Gratton, Steven
openaire   +2 more sources

Autonomous quantum thermal machine for generating steady-state entanglement [PDF]

open access: yes, 2015
We discuss a simple quantum thermal machine for the generation of steady-state entanglement between two interacting qubits. The machine is autonomous in the sense that it uses only incoherent interactions with thermal baths, but no source of coherence or
Jonatan Bohr Brask   +3 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Experimental Investigation of Debris-Induced Loading in Tsunami-Like Flood Events

open access: yesGeosciences, 2017
Debris loads during flood events have been well-documented by forensic engineering field surveys of affected communities. Research has primarily focused on debris impact loading and less emphasis has been placed into quantifying the loads and effects ...
Jacob Stolle   +6 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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