Results 61 to 70 of about 531,991 (267)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Analysis of transitional stresses in non-local thermo-elastic disc under steady state temperature
International Journal of Applied Mechanics and EngineeringIn solid mechanics, there are various applications of non-local theories in wave propagation, size effects, surface effects, and understanding interactions of composite materials.
Praveen Ailawalia +3 more
doaj +1 more source
Thermal Analysis of Power Semiconductor Device in Steady-State Conditions
Energies, 2019 Electronic devices can be damaged in an undesirable manner if the junction temperature achieves high values in order to cause thermal runaway and melting.
Adrian Plesca
doaj +1 more source
A Hydrodynamical Analysis of the Steady-State Shock Model [PDF]
The Open Astronomy Journal, 2009 9 pages, to be published in The Open Astronomy Journal ( http://www.bentham.org/open/toaaj/index.htm)
openaire +2 more sources
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Three-Phase Steady-State Model of Doubly Fed Induction Generator Considering Various Rotor Speeds
IEEE Access, 2016 This paper presents a new unbalanced steady-state model of doubly fed induction generator (DFIG) for the three-phase load flow analysis. The existing unbalanced DFIG steady-state model does not consider the effects of different rotor speeds. However, the
Yuntao Ju +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Fluids, 2019 This study explored two-dimensional (2D) numerical hydrodynamic model simulations of Lake Victoria. Several methods were developed in Matlab to build the lake topography.
Seema Paul +5 more
doaj +1 more source
Kinetic Modeling of Time-Dependent Enzyme Inhibition by Pre-Steady-State Analysis of Progress Curves: The Case Study of the Anti-Alzheimer's Drug Galantamine. [PDF]
Int J Mol Sci, 2022 Lamba D, Pesaresi A.
europepmc +1 more source