Results 81 to 90 of about 37,370,447 (302)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Steady-state Analysis of Doubly-fed Wind Power Generator

Kongzhi Yu Xinxi Jishu, 2010
It introduces the steady-state analysis of doubly-fed wind power generator based on the work conditions and the equivalent circuit, reckons the calculation process of the current on both stator side and rotor side.
郁灿, 金新民, 张禄, 战亮宇
doaj  

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Analysis of transitional stresses in non-local thermo-elastic disc under steady state temperature

International Journal of Applied Mechanics and Engineering
In solid mechanics, there are various applications of non-local theories in wave propagation, size effects, surface effects, and understanding interactions of composite materials.
Praveen Ailawalia, Ajay Bhiwal, Jatinder Kaur, Paweł Jurczak   +3 more
doaj   +1 more source

Thermal Analysis of Power Semiconductor Device in Steady-State Conditions

Energies, 2019
Electronic devices can be damaged in an undesirable manner if the junction temperature achieves high values in order to cause thermal runaway and melting.
Adrian Plesca
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Analogue mouse pointer control via an online steady state visual evoked potential (SSVEP) brain-computer interface [PDF]

, 2011
The steady state visual evoked protocol has recently become a popular paradigm in brain–computer interface (BCI) applications. Typically (regardless of function) these applications offer the user a binary selection of targets that perform correspondingly
Ramaswamy Palaniappan, John J Wilson, Wilson, John J., Palaniappan, Ramaswamy   +3 more
core   +1 more source

A Multi-Server Queuing Model With Balking and Correlated Reneging With Application in Health Care Management

IEEE Access, 2020
Queues or waiting lines are an integral part of health care facilities such as hospitals, outpatient clinics, medical laboratories, and many other health facilities. Health care management must have waiting lines control strategies for smooth functioning.
Godlove Suila Kuaban, Rakesh Kumar, Bhavneet Singh Soodan, Piotr Czekalski   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Steady-state performance analysis and modelling of directly driven interior permanent magnet wind generators

, 2011
Steady-state performance analysis and modelling of directly driven interior permanent magnet wind ...
SA Saleh (17322085), MASK Khan (17322088), Aziz Rahman (13059840)   +2 more
core   +1 more source