Results 131 to 140 of about 17,957,190 (298)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Replacement strategies in steady state genetic algorithms: Dynamic environments [PDF]
, 1999 Recent years have seen increasing numbers of applications of Evolutionary Algorithms to non-stationary environments such as on-line process control. Studies have indicated that Genetic Algorithms using "Steady State" models demonstrate a greater ability ...
Frantisek Vavak +3 more
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
DesignsThis paper presents a structured planning framework for the coordinated integration of photovoltaic (PV) systems and capacitor banks (CBs) in radial distribution networks to improve steady-state voltage regulation and reduce active-power losses.
Susan Murillo, Alexander Aguila Téllez
doaj +1 more source
Steady state errors and risk of a QC strategy
, 2019 Background: To minimise the risk of patient harm from results, laboratories should establish QC strategies and monitor the performance of assays in line with the analytical and clinical risk.
Badrick, Tony C, Mackay, Mark A
core +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Coordinated Frequency Regulation Strategy for Multi-Type Loads in High-Renewable Power Systems
EnergiesWith the increasing penetration of renewable energy, frequency stability issues in new-type power systems have become increasingly prominent due to reduced system inertia and weakened primary frequency regulation capability.
Zhenhua You +4 more
doaj +1 more source
A maximum entropy perspective reveals deviations from steady state during active diversification
Abstract Ecosystems are rarely at steady state, yet most theory predicting universal biodiversity patterns assumes they are. Here, we test whether and how eco-evolutionary dynamics drive departures from steady state by combining arthropod community data from the geologic chronosequence of the Hawaiian Archipelago with
Andrew J. Rominger +4 more
openaire +1 more source
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source