Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Engineering generalized Gibbs ensembles with trapped ions
Physical Review Research, 2021 The concept of generalized Gibbs ensembles (GGEs) has been introduced to describe steady states of integrable models. Recent advances show that GGEs can also be stabilized in nearly integrable quantum systems when driven by external fields and open. Here,
Florentin Reiter +5 more
doaj +1 more source
Maximum entropy approach to power-law distributions in coupled dynamic-stochastic systems
, 2006 Statistical properties of coupled dynamic-stochastic systems are studied within a combination of the maximum information principle and the superstatistical approach.
E. V. Vakarin +3 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Variable Tap-Length Algorithm with Mixed Parameter
Applied Sciences, 2018 Convergence speed and steady-state performance are important factors to estimate the variable tap-length algorithm. The step-size of tap-length (ST) and the error width considerably impact the performance of the fractional variable tap-length algorithm ...
Yufei Han, Mingjiang Wang, Yun Lu
doaj +1 more source
JacLy: a Jacobian-based method for the inference of metabolic interactions from the covariance of steady-state metabolome data [PDF]
PeerJ, 2018 Reverse engineering metabolome data to infer metabolic interactions is a challenging research topic. Here we introduce JacLy, a Jacobian-based method to infer metabolic interactions of small networks (
Mohammad Jafar Khatibipour +2 more
doaj +2 more sources
Detection of Single Ion Spectra by Coulomb Crystal Heating
, 2010 The coupled motion of ions in a radiofrequency trap has been used to connect the frequency- dependent laser-induced heating of a sympathetically cooled spectroscopy ion with changes in the fluorescence of a laser-cooled control ion.
C. Ricardo Viteri +6 more
core +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Steady state large deviations for one-dimensional, symmetric exclusion processes in weak contact with reservoirs [PDF]
, 2021 Angèle Bouley +2 more
openalex +1 more source
Respon Stabilitas Sistem Yang Menggunakan Governor Konvensional Dan Governor Fuzzy Logic [PDF]
, 2011 This paper aims to know how the conventional and fuzzy logic governor respons by load/disturbance changeand how the plant can achieve steady state condition after the load/disturbance change.
Arifin, Y. (Yusnaini)
core