Results 41 to 50 of about 438,567 (296)

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Tension thickening, molecular shape, and flow birefringence of an H-shaped polymer melt in steady shear and planar extension [PDF]

open access: yes, 2014
Despite recent advances in the design of extensional rheometers optimized for strain and stress controlled operation in steady, dynamic, and transient modes, obtaining reliable steady-state elongational data for macromolecular systems is still a ...
Baig, Chunggi, Mavrantzas, Vlasis G.
core   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Analysis of Methods for Leak Detection and Monitoring the Main Gas Pipeline Sections

open access: yesEnergy Engineering and Control Systems
The paper analyzes the existing methods for leak detection and monitoring the main gas pipeline sections. An extended classification of methods is presented based on the additional parameters: operating mode (steady-state, non-steady-state) and type of ...
Bohdan Danyltsiv, Olha Khymko
doaj   +1 more source

Sensor-fault tolerance using robust MPC with set-based state estimation and active fault isolation [PDF]

open access: yes, 2014
In this paper, a sensor fault-tolerant control (FTC) scheme using robust model predictive control (MPC) and set theoretic fault detection and isolation (FDI) is proposed.
Niculescu, Silviu-Iulian   +4 more
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Probabilistic Steady-State Operation and Interaction Analysis of Integrated Electricity, Gas and Heating Systems

open access: yesEnergies, 2018
The existing studies on probabilistic steady-state analysis of integrated energy systems (IES) are limited to integrated electricity and gas networks or integrated electricity and heating networks.
Lun Yang, Xia Zhao, Xinyi Li, Wei Yan
doaj   +1 more source

Steady-state analysis of self-excited induction generators using genetic algorithm approach under different operating modes

open access: yesInternational Journal of Sustainable Energy, 2013
The main focus of this paper is the steady-state analysis of self-excited induction generators (SEIGs). It employs the genetic algorithm approach (GAA) to estimate the steady-state performance of these machines. Further, the GAA is used for the solution of problems related to the operation of a number of SEIGs running in parallel. GA-based modelling is
Joshi, Dheeraj   +2 more
openaire   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Towards detachment-compatible I-mode plasma on EAST tokamak

open access: yesNuclear Fusion
The divertor detachment is important for the improved confinement mode (I-mode) to serve as a reliable operating scenario in future fusion reactors. A reproducible steady-state I-mode operation with the energy detachment of the inner target has been ...
L. Yu   +25 more
doaj   +1 more source

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