Results 61 to 70 of about 440,835 (294)
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
LLC resonant converters have been widely adopted in many different industrial applications due to their characteristics of high efficiency and high power density. Simulation tools are of great importance for the analysis and design of LLC resonant converters.
Yuqi Wei +3 more
openaire +2 more sources
Robust MPC for actuator-fault tolerance using set-based passive fault detection and active fault isolation [PDF]
In this paper, an actuator fault-tolerant control (FTC) scheme is proposed, which is based on tube-based model predictive control (MPC) and set-theoretic fault detection and isolation (FDI). As a robust MPC technique, tube-based MPC, can effectively deal
Niculescu, Silviu-Iulian +4 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Operation Modes of a Secondary-Side Phase-Shifted Resonant Converter
In this work, a unidirectional full-bridge resonant converter with secondary-side phase-shifted control is addressed. With the variation of voltage gain and power level, this converter may enter into different operational modes, including three ...
Song Hu +3 more
doaj +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Improved Energy Balance Control for Boost Converters Without Estimating Circuit Energy Losses
The previously developed control methods based on the conservation of energy in circuits require the accurate estimation of energy losses, which is difficult to measure and calculate for boost converters.
Lei Wang, Qinghua Wu, Wenhu Tang
doaj +1 more source
Single- and Multi-Objective Optimization of a Dual-Chamber Microbial Fuel Cell Operating in Continuous-Flow Mode at Steady State [PDF]
Microbial fuel cells (MFCs) are a promising technology for bioenergy generation and wastewater treatment. Various parameters affect the performance of dual-chamber MFCs, such as substrate flow rate and concentration. Performance can be assessed by power density ( PD ), current density ( CD ) production, or substrate removal efficiency ...
openaire +3 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Modeling of cone crusher steady-state operation modes
Abstract The design of complex technological processes control systems involves several stages. One of the first is to analyze the steady-state operation modes of the control plant. Ore crushing is one of the most critical processes in mineral processing.
openaire +1 more source

