Results 81 to 90 of about 48,477 (300)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Thin-disk laser – Power scaling to the kW regime in fundamental mode operation

, 2009
A significant reduction of the influence of the thermal lens in thin-disk lasers in high power laser operation mode could be achieved, using dynamically stable resonators. For designing the resonator, investigations of thermally induced phase distortions
Schmid, Elke, Speiser, Jochen, Giesen, Adolf, Spindler, Gerhard, Mende, Jens   +4 more
core  

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Fast transition from pump to turbine mode of operation [PDF]

, 2018
The reversible pump turbine (RPT) is a suitable machine to control fluctuations in the energy market. The usage of RPTs for this purpose will increase the number of operational mode changes of the machine.
Nielsen, Torbjørn Kristian, Svarstad, Magni Fjørtoft   +1 more
core   +2 more sources

A steady-state L-mode tokamak fusion reactor : large scale and minimum scale [PDF]

, 2010
Thesis (S.B.)--Massachusetts Institute of Technology, Dept. of Physics, June 2010.Cataloged from PDF version of thesis.Includes bibliographical references (p.
Reed, Mark W. (Mark Wilbert)
core  

Synchronous mode operation in electrical machine with DC stator excitation

, 2013
In transport applications, the synchronous motors are used for the power drives, because of their high operating efficiency, and controllable power factor.
Okrainskaya I., Gladyshev S.P.
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Nanoparticle emissions from a fleet of CNG buses in transient and steady state operation

, 2006
Particle emission measurements from a fleet of 14 CNG and 5 Diesel buses were measured both for transient and steady state mode\ud s on a chassis dynamometer with a CVS dilution system. Several transient DT80 cycles and 4 steady sate modes (0, 25, 50 100%
Morawska, Lidia, Jayaratne, Rohan, Weitten, Oliver, Ristovski, Zoran, Meyer, Nickolas K.   +4 more
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source