Results 71 to 80 of about 440,835 (294)

Dynamic modal analysis of monolithic mode-locked semiconductor lasers [PDF]

open access: yes, 2003
We analyze the advantages and applicability limits of the mode-coupling approach to active, passive, hybrid, and harmonic mode-locking in diode lasers. A simple, computationally efficient numerical model is proposed and applied to several traditional and
Arnold, J.M.   +2 more
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Comparison of Carbonyls and BTEX Emissions from a Light Duty Vehicle Fuelled with Gasoline and Ethanol-Gasoline Blend, and Operated without 3-Way Catalytic Converter [PDF]

open access: yesMehran University Research Journal of Engineering and Technology, 2011
This paper presents the comparison of unregulated emissions such as carbonyls and BTEX (Benzene, Toluene, Ethyl Benzene, and Xylenes) species emanated from a light duty SI (Spark Ignition) vehicle E-0 (fuelled on gasoline) and E-10 (ethanol-gasoline ...
Asad Naeem Shah   +2 more
doaj  

Active distribution network with efficient utilisation of distributed generation ancillary

open access: yesIET Smart Grid, 2018
This study introduces an active distribution network with high penetration of inverter-based distributed generations (IBDGs) to improve the steady state, dynamic and transient performance of the distribution network.
Desmond O. Ampofo   +2 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Timing and Operating Mode Design for Time-Gated Fluorescence Lifetime Imaging Microscopy

open access: yesThe Scientific World Journal, 2013
Steady-state fluorence imaging and time-resolved fluorescence imaging are two important areas in fluorescence imaging research. Fluorescence lifetime imaging is an absolute measurement method which is independent of excitation laser intensity ...
Chao Liu   +3 more
doaj   +1 more source

REDO RSVP: Efficient Signalling for Multimedia in the Internet [PDF]

open access: yes, 1999
Alarming reports of performance and scalability problems associated with per-flow reservations, have led many to lose belief in RSVP and the Integrated Services Architecture that relies on it.
Hutchison, David   +3 more
core   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Operation and Testing of Indirect Field Oriented Control of Asymmetrical Six-Phase Open-Ended Winding Induction Machine Using Hardware-in-Loop (HIL) Emulator

open access: yesInternational Transactions on Electrical Energy Systems, 2023
This study deals with an asymmetrical six-phase open-ended winding induction machine in closed loop operation using indirect field-oriented control scheme.
Arif Iqbal   +2 more
doaj   +1 more source

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