Results 131 to 140 of about 2,668,180 (336)

Enhancement of Transient and Steady State Responses of Voltage by Using DVR [PDF]

, 2013
Jyothilal Nayak Bharothu
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Stability and bifurcation of steady-state solutions for predator-prey equations

, 1982
Edward D. Conway, Rod Gardner, Joel Smoller   +2 more
openalex   +2 more sources

Steady State Creep Characteristics of Sn-5wt% Sb-(0.5-3) wt% Ag Solders [PDF]

, 2017
M.I. Sobhy, A El-Refai, D Shnawah, S Said, M Sabri, I Badruddin, F Che, F Che, J Pang, Q Bui, S Jung, M Kangooie, R Mahmudi, A Geranmayeh, H Lee, H Lin, C Lee, P Chen, R Mahmudi, A Geranmayeh, M Bakherad, M Allami, H Rhee, K Subramanian, A Lee, G Lee, Sw Chen, Chen, W Gierlotka, A Zi, P Chen, H Wu, C Cy Lin, X Lee, Liu, Yen Yw, A El-Daly, A Mohamad, A Fawzy, A El-Taher, Guang Zeng, Stuart Mcdonald, Kazuhiro Nogita, A Fawzy, S Fayek, M Sobhy, E Nassr, M Mousa, G Saad, M Alam, S Nai, M Gupta, P Liu, P Yao, J Liu, S Chang, C Jain, T Chuang, L Feng, L Tsao, A El-Daly, A Fawzy, S Mansour, M Younis, F Tai, Fu Guo, Zhi-Dong Xia, Yong-Ping Lei, Yao-Wu Shi, Y Shi, P Liu, Y Yan, Z Xia, Y Lei, F Guo, A El-Daly, A Fawzy, A Mohamad, A El-Taher, P Babaghorbani, S Nai, M Gupta, A Haseeb, M Arafat, M Johan, A El-Daly, Y Swilem, M Makled, M El-Shaarawy, A Abdraboh, A El-Daly, S Choi, J Lee, F Guo, T Bieler, K Subramanian, J Lucas, M Huang, C Wu, L Wang   +99 more
openalex   +1 more source

Developed steady-state response for a new hybrid damper mounted on structures

, 2023
Mohammad Ziaee, Farzad Hejazi
openalex   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Tight Bounds on the Expected Runtime of a Standard Steady State Genetic Algorithm [PDF]

, 2021
Pietro S. Oliveto, Dirk Sudholt, Carsten Witt   +2 more
openalex   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

A conservative implicit scheme for steady state solutions of diatomic gas flow in all flow regimes [PDF]

, 2019
Ruifeng Yuan, Chengwen Zhong
openalex   +1 more source