Results 121 to 130 of about 28,220,041 (343)

A Steady State ANN Model for the Operational Characteristics of a Variable Speed (VS) Direct Expansion (DX) Air Conditioning (A/C) System

open access: yesZhileng xuebao, 2017
In this study, an ANN model for an experimental VS DX A/C system was developed to predict its outputs with an assumption that the indoor air states will not influence the relative value of system outputs. Steady state experiments under a fixed indoor air
Li Zhao, Deng Shiming
doaj  

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

CovingtonResearchGroup/ESURF-Steady-state-layered-rocks: First release of materials used in Perne et al. (2017).

open access: yes, 2017
<p>This is the archive of simulation inputs and python scripts used in the manuscript Perne, M., Covington, M.D., Thaler, E.A., and J.M. Myre (2017).
Matt Covington
core   +1 more source

Brown and Levy Steady-State Motions

open access: yesEntropy
This paper introduces and explores a novel class of Brown and Levy steady-state motions. These motions generalize, respectively, the Ornstein-Uhlenbeck process (OUP) and the Levy-driven OUP.
Iddo Eliazar
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Sex-Related Differences in the Maximal Lactate Steady State

open access: yesSports, 2018
The maximal lactate steady state (MLSS) is one of the factors that differentiates performance in aerobic events. The purpose of this study was to investigate the sex differences in oxygen consumption (VO2), heart rate (HR), and the respiratory exchange ...
Paul S. Hafen, Pat R. Vehrs
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Analogue mouse pointer control via an online steady state visual evoked potential (SSVEP) brain-computer interface [PDF]

open access: yes, 2011
The steady state visual evoked protocol has recently become a popular paradigm in brain–computer interface (BCI) applications. Typically (regardless of function) these applications offer the user a binary selection of targets that perform correspondingly
Ramaswamy Palaniappan   +3 more
core   +1 more source

Pre-Steady-State and Steady-State Kinetic Analysis of Butyrylcholinesterase-Catalyzed Hydrolysis of Mirabegron, an Arylacylamide Drug

open access: yesMolecules
The β-adrenergic drug Mirabegron, a drug initially used for the treatment of an overactive bladder, has new potential indications and is hydrolyzed by butyrylcholinesterase (BChE).
Zukhra Shaihutdinova, Patrick Masson
doaj   +1 more source

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