Results 121 to 130 of about 2,680,718 (334)

Optimal Cyclical Monetary Policy: Does Steady-State Inflation Matter? [PDF]

In general equilibrium models, optimal cyclical monetary policy is usually derived around an optimal steady-state inflation level, which in most cases is zero or equal to the negative of the real interest rate.
Samuel Reynard
core  

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Decision letter for "PSPManalysis: Steady‐state and bifurcation analysis of physiologically structured population models"

, 2020

openalex   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Steady state analysis of balanced-allocation routing

, 2002
We compare the long-term, steady-state performance of a variant of the standard Dynamic Alternative Routing (DAR) technique commonly used in telephone and ATM networks, to the performance of a path-selection algorithm based on the "balanced-allocation ...
Anagnostopoulos, Aris, Kontoyiannis, Ioannis, Upfal, Eli   +2 more
core   +1 more source

Steady State Creep Characteristics of Sn-5wt% Sb-(0.5-3) wt% Ag Solders [PDF]

, 2017
M.I. Sobhy, A El-Refai, D Shnawah, S Said, M Sabri, I Badruddin, F Che, F Che, J Pang, Q Bui, S Jung, M Kangooie, R Mahmudi, A Geranmayeh, H Lee, H Lin, C Lee, P Chen, R Mahmudi, A Geranmayeh, M Bakherad, M Allami, H Rhee, K Subramanian, A Lee, G Lee, Sw Chen, Chen, W Gierlotka, A Zi, P Chen, H Wu, C Cy Lin, X Lee, Liu, Yen Yw, A El-Daly, A Mohamad, A Fawzy, A El-Taher, Guang Zeng, Stuart Mcdonald, Kazuhiro Nogita, A Fawzy, S Fayek, M Sobhy, E Nassr, M Mousa, G Saad, M Alam, S Nai, M Gupta, P Liu, P Yao, J Liu, S Chang, C Jain, T Chuang, L Feng, L Tsao, A El-Daly, A Fawzy, S Mansour, M Younis, F Tai, Fu Guo, Zhi-Dong Xia, Yong-Ping Lei, Yao-Wu Shi, Y Shi, P Liu, Y Yan, Z Xia, Y Lei, F Guo, A El-Daly, A Fawzy, A Mohamad, A El-Taher, P Babaghorbani, S Nai, M Gupta, A Haseeb, M Arafat, M Johan, A El-Daly, Y Swilem, M Makled, M El-Shaarawy, A Abdraboh, A El-Daly, S Choi, J Lee, F Guo, T Bieler, K Subramanian, J Lucas, M Huang, C Wu, L Wang   +99 more
openalex   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Steady-state shocks in an accretion disc around a Kerr black hole [PDF]

, 1994
H. Sponholz, D. Molteni
openalex   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source