Results 121 to 130 of about 871,293 (307)
Sex-Related Differences in the Maximal Lactate Steady State
Sports, 2018 The maximal lactate steady state (MLSS) is one of the factors that differentiates performance in aerobic events. The purpose of this study was to investigate the sex differences in oxygen consumption (VO2), heart rate (HR), and the respiratory exchange ...
Paul S. Hafen, Pat R. Vehrs
doaj +1 more source
Steady-state gain for mw at selected operating conditions.
, 2020 Steady-state gain for mw at selected operating conditions.
Abdullah Najib (5832470) +2 more
core +1 more source
α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates
FEBS Letters, EarlyView.Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
V˙O2 linear-onset kinetics spanning steady- and non-steady-state exercise
Frontiers in PhysiologyIntroductionThe traditional method for quantifying the kinetics of the increase in the body’s consumption of oxygen (V˙O2) during exercise transitions to steady state involves application of a mono-exponential function.
Robert Robergs +7 more
doaj +1 more source
, 2020 (A) Volcano plots of steady-state changes of metabolites. The threshold for Type I error (α) is 0.05, with p-value corrected for multiple testing hypothesis (see Materials and Methods), and for a relevant fold-change is 30% difference from initial steady-
Manuel J. T. Carrondo (7380635) +7 more
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Steady-state kinetic parameters of OTC and its variants with respect to ornithine.
, 2020 Steady-state kinetic parameters of OTC and its variants with respect to ornithine.
Kevin E. Ramos (8415567) +8 more
core +1 more source
FEBS Letters, EarlyView.Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley +1 more source