Results 121 to 130 of about 18,641,062 (303)
Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
FEBS Letters, EarlyView.Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Steady-state butanol productivity as a function of dilution rate and culture pH.
, 2016 Steady-state butanol productivity as a function of dilution rate and culture pH.
Edward A. Buehler (3144129) +1 more
core +1 more source
V˙O2 linear-onset kinetics spanning steady- and non-steady-state exercise
Frontiers in PhysiologyIntroductionThe traditional method for quantifying the kinetics of the increase in the body’s consumption of oxygen (V˙O2) during exercise transitions to steady state involves application of a mono-exponential function.
Robert Robergs +7 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Steady-state concentrations of cytokines, macrophages and T cells in a healthy individual.
, 2016 Steady-state concentrations of cytokines, macrophages and T cells in a healthy individual.
Violeta Arsenescu (2541487) +3 more
core +1 more source
The ubiquitin system in normal and infected germinal center B cells
FEBS Letters, EarlyView.The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis +2 more
wiley +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Steady-state transcriptional pattern is well predicted from the transient response
, 2011 Copyright information:Taken from "Genome-wide transcriptional plasticity underlies cellular adaptation to novel challenge"Molecular Systems Biology 2007;3():106-106.Published online 24 Apr 2007PMCID:PMC1865588.Copyright © 2007, EMBO and Nature Publishing
Naama Brenner (28701) +4 more
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source