Results 101 to 110 of about 18,641,062 (303)
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Steady-state kinetic parameters of OTC and its variants with respect to carbamoyl phosphate.
, 2020 Steady-state kinetic parameters of OTC and its variants with respect to carbamoyl phosphate.
Kevin E. Ramos (8415567) +8 more
core +1 more source
Unconventional abdominal uses of FIESTA (CISS) sequence
Indian Journal of Radiology and Imaging, 2013 The ability to provide cross-sectional imaging, combined with a lack of ionizing radiation has made magnetic resonance imaging (MRI) of abdomen popular. We report four interesting cases: Midgut malrotation with volvulus, sigmoid volvulus, biliary rupture
Anitha Sen
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Frontiers in Systems NeuroscienceTranscranial alternating current stimulation (tACS) is a non-invasive technique that modulates brain oscillatory activity in a frequency-specific manner, offering potential for improving sensory and cognitive functions.
Aurimas Mockevičius +4 more
doaj +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Structural and biochemical analysis of a B12 superbinder
FEBS Letters, EarlyView.BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices +3 more
wiley +1 more source
Steady-state kinetic parameters of the most potent inhibitors of EcaGST A3-3.
, 2019 Steady-state kinetic parameters of the most potent inhibitors of EcaGST A3-3.
Helena Lindström (6494582) +3 more
core +1 more source
, 2023 <p>Version 2.0 of GEOCLIM-DynSoil-steady-state with input and configuration files used for the experiments presented in "The Role of Southeast Asian Island Topography on Indo-Pacific Climate and Silicate Weathering" (Chiang et al ...
Yuem Park +3 more
core +1 more source
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source