Results 131 to 140 of about 871,293 (307)

Steady-state transcriptional pattern is well predicted from the transient response

, 2011
Copyright information:Taken from "Genome-wide transcriptional plasticity underlies cellular adaptation to novel challenge"Molecular Systems Biology 2007;3():106-106.Published online 24 Apr 2007PMCID:PMC1865588.Copyright © 2007, EMBO and Nature Publishing
Naama Brenner (28701), Erez Braun (28702), Tali Dror (28699), Elad Stolovicki (28700), Shay Stern (28698)   +4 more
core   +1 more source

Steady-state kinetic parameters of recombinant TsTPI and SmTPI in comparison to HsTPI.

, 2020
Steady-state kinetic parameters of recombinant TsTPI and SmTPI in comparison to HsTPI.
Pedro Jimenez-Sandoval (831603), Lucia Leyva-Navarro (8283546), Corina Díaz-Quezada (6010490), Misraim Gurrola (8283540), Laura D. Camacho-Manriquez (8283543), Rogelio González-González (8283537), Luis G. Brieba (115741), Eduardo Castro-Torres (6010475)   +7 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Steady-State Electrochemiluminescence at Single Semiconductive Titanium Dioxide Nanoparticles for Local Sensing of Single Cells

, 2018
Obtaining steady-state bright electrochemiluminescence (ECL) at single nanoparticles is crucial but challenging for the realization of the single-nanoparticle electrochemical sensing of single cells.
Jun-Jie Zhu, Hong-Yuan Chen, Jun-Jie Zhu (1329426), Ying Chen (9697), Jianrong Zhang (408805), Chen Cui, Dechen Jiang (1406383), Chen Cui (2376928), Dechen Jiang, Ying Chen, Jianrong Zhang, Hong-Yuan Chen (1400701)   +11 more
core   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Steady-states design.

, 2019
Participants underwent a set of separate task-based (visual, motor and visuomotor) or task-free (resting) steady-state scans, each acquisition lasting five minutes.
Tamar R. Makin (6577229), Nicola Filippini (2578129), Eugene P. Duff (1369455), Paulina Kieliba (6577226), Sasidhar Madugula (4588804)   +4 more
core   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Replacement strategies in steady state genetic algorithms: Dynamic environments [PDF]

, 1999
Recent years have seen increasing numbers of applications of Evolutionary Algorithms to non-stationary environments such as on-line process control. Studies have indicated that Genetic Algorithms using "Steady State" models demonstrate a greater ability ...
Frantisek Vavak, Smith, Jim, Jim E. Smith, Vavak, F.   +3 more
core  

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Steady-state solution of a fully coupled system in the limit of large D.

, 2016
As in Fig 2, the near steady-state solution of a fully coupled system was obtained by VCell hybrid for the fast-diffusion limit and validated against Gibson-Bruck stochastic nonspatial solver. Results from each solver are based on 20,000 realizations and
Fei Gao (29262), Igor L. Novak (3396206), Boris M. Slepchenko (464480), James C. Schaff (3396203), Ye Li (290115)   +4 more
core   +1 more source