Results 161 to 170 of about 2,680,718 (334)

Supplementary Material for: Signal Alteration of the Inner Ear on High-Resolution Three-Dimensional Constructive Interference in Steady State Sequence in Patients with Ménière’s Disease and Labyrinthitis

, 2022
Arsany Hakim, Hool S.-L., Nabil A. Yassa, Breiding P.S., Manuela Pastore‐Wapp, Marco Caversaccio, Lukas Anschuetz, Franca Wagner   +7 more
openalex   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A robust clustering method for detection of abnormal situations in a process with multiple steady-state operation modes

, 2009
Mauricio Maestri, Andrés Farall, Pablo Groisman, Miryan Cassanello, Gabriel Horowitz   +4 more
openalex   +2 more sources

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

LHD Diagnostics Toward Steady-State Operation

, 2004
S. Sudo, B. J. Peterson, K. Kawahata, Y. Nagayama, K. Narihara, Yoshinori Hamada, K. Toi, K. Ida, H. Iguchi, K. Sato, S. Morita, T. Ozaki, A. Nishizawa, K. Tanaka, T. Minami, I. Yamada, S. Mutoh, M. Emoto, H. Nakanishi, M. Goto, S. Ohdachi, T. Tokuzawa, S. Inagaki, T. Ido, M. Yoshinuma, S. Sakakibara, S. Masuzaki, T. Morisaki, M. Shoji, M. Osakabe, N. Ashikawa   +30 more
openalex   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Measuring low gas permeability of granites: A comparative assessment of Quasi‑Steady‑State and Pulse‑Test Methods

Gay, Nicolas
openalex   +1 more source

ANALYSIS OF WEB-PROXY CACHE REPLACEMENT ALGORITHMS UNDER STEADY-STATE CONDITIONS

, 2007
L.G. Cardenas, Ana Pont, Julio Sahuquillo, José A. Gil   +3 more
openalex   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source