Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Clinical and laboratory characteristics of adolescents and young adults with sickle cell disease at steady state in Uganda. [PDF]
Ssekandi AM +12 more
europepmc +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
Steady-state mobilization with on-demand plerixafor after CD38 antibody-based induction in multiple myeloma patients. [PDF]
Röhnert MA +13 more
europepmc +1 more source
Development of a plant-wide steady-state wastewater treatment plant design and analysis program
William Ying Xin Wu
openalex +1 more source
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
A Retrospective Within-Subjects Analysis of Vancomycin Bayesian Modeling With Pre-steady-State vs Steady-State Concentrations. [PDF]
Covington EW, Chae JL, Gunter SG.
europepmc +1 more source
Steady-state and emergency dendritic cell development at a clonal level
Shuiping Lin
openalex +1 more source
Dynamic modeling and sensitivity analysis of dAFM in the transient and steady state motions
Amir Farokh Payam
openalex +2 more sources

