A detailed workflow for recombinant GALC production and characterization is presented to support enzyme replacement therapy for Krabbe disease. In vitro assays demonstrate that physiological GALC doses restore enzymatic activity and autophagic flux without affecting cell viability, whereas higher doses impair autophagy and reduce viability.
Ambra Del Grosso+5 more
wiley +1 more source
Numerical Analysis of Steady-State Multi-Field Coupling in Electro-Fused Magnesia Furnace. [PDF]
Weng C, Wang Z, Luo X, Li H.
europepmc +1 more source
Phase Locking of 40 Hz Auditory Steady State Responses Is Modulated by Sensory Predictability and Linked to Cerebellar Myelination. [PDF]
Larsen KM+5 more
europepmc +1 more source
AISI 304L stainless steel powder is mixed with silicon nitride (Si3N4) powder and processed by PBF‐LB/M, allowing partial retention of Si3N4. The numerical approach effectively predicts the Si3N4 powder homogeneity and N content distribution on the powder bed. Recent studies have focused on the alloying of nitrogen (N) in high‐alloy stainless steels by
Yuanbin Deng+7 more
wiley +1 more source
Navigating Vancomycin and Acute Kidney Injury: AUC- vs. Trough-Guided Monitoring in Initial and Steady-State Therapy. [PDF]
Marovič A, Vovk T, Petre M.
europepmc +1 more source
Hydrogel‐Based Capacitive Sensor Model for Ammonium Monitoring in Aquaculture
Traditional techniques for monitoring aquaculture water quality, particularly ammonium levels, harm fish. This work presents a novel capacitive sensor with an ionic hydrogel transducer to monitor ammonium concentration in real time based on the ammonium‐induced hydrogel dissociation and osmotic pressure. Monitoring aquaculture water quality, especially
Mohammad Mirzaee+3 more
wiley +1 more source
Active Osseointegrated Steady-State Implant System: Surgical and Clinical Performance. [PDF]
Ordoñez-Ordoñez L+9 more
europepmc +1 more source
In this study, exciting new bi‐/multi‐linear elastic behavior of soft elastic composites that accompany the activation of wrinkling in the embedded interfacial layers is analyzed. The new features and performance of these composite materials, including dramatic enhancements in energy storage, can be tailored by the concentration of interfacial layers ...
Narges Kaynia+2 more
wiley +1 more source
Magnetic Resonance Imaging of the Peripheral Nerves and Fascicles of the Knee Using Double Echo Steady State Sequence at 7 Tesla. [PDF]
Chen P+14 more
europepmc +1 more source
Studies on Crystal Size Distributions in Continuous Steady State Mixed Suspension Crystallizer
Terukatsu Miyauchi, Hiroshi Imai
openalex +2 more sources