Results 31 to 40 of about 622,364 (312)
Characterization of the prostate-specific antigen (PSA) catalytic mechanism: a pre-steady-state and steady-state study. [PDF]
PLoS ONE, 2014 Prostate-specific antigen (PSA), an enzyme of 30 kDa grouped in the kallikrein family is synthesized to high levels by normal and malignant prostate epithelial cells.
Luigi Tomao +6 more
doaj +1 more source
Dendritic cells steering antigen and leukocyte traffic in lymph nodes
FEBS Letters, EarlyView.Dendritic cells are key players in the activation of T cells and their commitment to effector function. In this In a Nutshell Review, we will discuss how dendritic cells guide the trafficking of antigen and leukocytes in the lymph node, thus influencing T‐cell activation processes. Dendritic cells (DCs) play a central role in initiating and shaping the
Enrico Dotta +3 more
wiley +1 more source
The dual nature of TDC – bridging dendritic and T cells in immunity
FEBS Letters, EarlyView.TDC are hematopoietic cells combining dendritic and T cell features. They reach secondary lymphoid organs (SLOs) and peripheral organs (liver and lungs) after FLT3‐dependent development in the bone marrow and maturation in the thymus. TDC are activated and enriched in SLOs upon viral infection, suggesting that they might play unique immune roles, since
Maria Nelli, Mirela Kuka
wiley +1 more source
Envisioning a Successful Steady-State Economy
The Journal of Population and Sustainability, 2018 There are two interacting types of argument for a steady-state economy: its biopyhsical necessity, and its ethical desirability. The first argument is made in terms of the finitude, entropy, and physical maintenance requirements of “dissipative ...
Herman Daly
doaj +1 more source
FEBS Letters, EarlyView.In vivo IL‐10 produced by tissue‐resident tolDC is involved in maintaining/inducing tolerance. Depending on the agent used for ex vivo tolDC generation, cells acquire common features but prime T cells towards anergy, FOXP3+ Tregs, or Tr1 cells according to the levels of IL‐10 produced. Ex vivo‐induced tolDC were administered to patients to re‐establish/
Konstantina Morali +3 more
wiley +1 more source
SPECIALIZED SYMBOLIC COMPUTATION FOR STEADY STATE PROBLEMS
Informatyka, Automatyka, Pomiary w Gospodarce i Ochronie Środowiska, 2013 An implementation of symbolic computation for steady state problems is proposed in the paper. A mathematical basis is derived in order to specify the quantities that the implementation will concern.
Marcin Sowa
doaj +1 more source
Graphical Presentation of the Steady-state Economy Model
The Journal of Population and Sustainability, 2022 There are several theories claiming that their policies can save the planet from environmental catastrophe. This paper claims that it is only the Steady-State Economy model on which such reasonably effective expectations can be based.
Theodore Lianos
doaj +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source
Steady State Economy at Optimal Population Size
The Journal of Population and Sustainability, 2018 This paper reviews briefly the idea of a steady state economy from the ancient times to the present. It discusses some of the suggestions made by H. Daly in his model of a steady state economy and particularly the idea of a stable population. It suggests
Theodore Lianos
doaj +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source