Results 91 to 100 of about 513,877 (318)

Numerical Study on Flow and Heat Transfer of Alkali Metal High-temperature Heat Pipe during Frozen Startup Based on FVM

Yuanzineng kexue jishu
In recent years, heat pipe has been widely used as an efficient heat transfer equipment in fuel chemistry, electronic communication and so on. The main structure of a heat pipe mainly includes the vacuum tube containing alkali metal working fluid and ...
ZHAO Haocheng, ZHANG Zeqin, WANG Chenglong, QIU Suizheng, TIAN Wenxi, SU Guanghui
doaj   +1 more source

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

Molecular Oncology, Volume 19, Issue 7, Page 1979-1997, July 2025.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi, Jérome Vialaret, Christophe Hirtz, Catherine Alix‐Panabières   +3 more
wiley   +1 more source

Clinical applications of next‐generation sequencing‐based ctDNA analyses in breast cancer: defining treatment targets and dynamic changes during disease progression

Molecular Oncology, Volume 19, Issue 7, Page 1897-1917, July 2025.
Circulating tumor DNA (ctDNA) offers a possibility for different applications in early and late stage breast cancer management. In early breast cancer tumor informed approaches are increasingly used for detecting molecular residual disease (MRD) and early recurrence. In advanced stage, ctDNA provides a possibility for monitoring disease progression and
Eva Valentina Klocker, Samantha Hasenleithner, Rupert Bartsch, Simon P. Gampenrieder, Daniel Egle, Christian F. Singer, Gabriel Rinnerthaler, Michael Hubalek, Katja Schmitz, Zsuzsanna Bago‐Horvath, Andreas Petzer, Sonja Heibl, Ellen Heitzer, Marija Balic, Michael Gnant   +14 more
wiley   +1 more source

MET variants with activating N‐lobe mutations identified in hereditary papillary renal cell carcinomas still require ligand stimulation

Molecular Oncology, EarlyView.
MET variants in the N‐lobe of the kinase domain, found in hereditary papillary renal cell carcinoma, require ligand stimulation to promote cell transformation, in contrast to other RTK variants. This suggests that HGF expression in the microenvironment is important for tumor growth in such patients. Their sensitivity to MET inhibitors opens the way for
Célia Guérin, Audrey Vinchent, Marie Fernandes, Isabelle Damour, Agathe Laratte, Rémi Tellier, Gabriella O. Estevam, Jean‐Pascal Meneboo, Céline Villenet, Clotilde Descarpentries, James S. Fraser, Martin Figeac, Alexis B. Cortot, Etienne Rouleau, David Tulasne   +14 more
wiley   +1 more source

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

Molecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé, Lisa Hahnefeld, Katharina J. Wenger, Donat Kögel, Joachim Steinbach, Gerd Geisslinger, Michael W. Ronellenfitsch, Irmgard Tegeder   +7 more
wiley   +1 more source

Deuterium plasma induced preferential erosion in ultra-high temperature ceramics TiB2 and ZrB2

Nuclear Fusion
Steady-state deuterium plasma exposures were performed on ultra-high temperature ceramics titanium diboride (TiB _2 ) and zirconium diboride (ZrB _2 ) using the PISCES-RF linear plasma device (LPD) as early screening for first wall, plasma-facing ...
L. Nuckols, M.J. Baldwin, H.M. Meyer III, D. Nishijima, M.I. Patino, C.M. Parish, J. Rapp   +6 more
doaj   +1 more source

The Structure of the Hadron-Quark Combustion Zone

Universe, 2019
Hadron-quark combustion in dense matter is a central topic in the study of phases in compact stars and their high-energy astrophysics. We critically reviewed the literature on hadron-quark combustion, dividing them into a “first wave” that ...
Amir Ouyed, Rachid Ouyed, Prashanth Jaikumar   +2 more
doaj   +1 more source

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

Molecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak, Żaneta Zarębska, Marcin P. Sajek, Adriana Grabowska, Alessia Buratin, Paweł Głodowicz, Julia O. Misiorek, Konrad Kuczyński, Stefania Bortoluzzi, Marek Żywicki, Jan G. Kosiński, Agnieszka Rybak‐Wolf, Rafał Piestrzeniewicz, Anna M. Barciszewska, Katarzyna Rolle   +14 more
wiley   +1 more source

Investigation of the Uniformity of Gel Shrinkage by Imaging Tracer Particles Using X‐Ray Microtomography

Advanced Engineering Materials, EarlyView., 2023
A novel method for tracking structural changes in gels using widely accessible microcomputed tomography is presented and validated for various hydro‐, alco‐, and aerogels. The core idea of the method is to track positions of micrometer‐sized tracer particles entrapped in the gel and relate them to the density of the gel network.
Anja Hajnal, Mimololorun Lucy Aiyelari, Martin Dirauf, Pavel Gurikov   +3 more
wiley   +1 more source

Dielectrically Monitored Flow Synthesis of Functional Vaccine Adjuvant Mixtures via Microwave-Assisted Catalytic Chain Transfer Processing

Chemistry
A novel flow process to produce low-molecular-weight (Mwt) methacrylate oligomer mixtures that have potential as vaccine adjuvants and chain transfer agents (CTAs) is reported. The chemistry and process were designed to significantly reduce the number of
Cordula S. Hege, Ian E. Hamilton, Adam A. Dundas, Kevin Adlington, Edward Walker, Helena Henke, Kaiyang Wang, Georgios Dimitrakis, Adam Buttress, Christopher Dodds, Christopher B. Fox, Derek J. Irvine   +11 more
doaj   +1 more source