Results 71 to 80 of about 539,119 (298)

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Transient fluctuation-induced forces in driven electrolytes after an electric field quench

New Journal of Physics, 2021
Understanding how electrolyte solutions behave out of thermal equilibrium is a long-standing endeavor in many areas of chemistry and biology. Although mean-field theories are widely used to model the dynamics of electrolytes, it is also important to ...
Saeed Mahdisoltani, Ramin Golestanian
doaj   +1 more source

Photochemistry in the arctic free troposphere: Ozone budget and its dependence on nitrogen oxides and the production rate of free radicals [PDF]

, 2004
. Local ozone production and loss rates for the arctic free troposphere (58–85 ◦ N, 1–6 km, February–May) during the Tropospheric Ozone Production about the Spring Equinox (TOPSE) campaign were calculated using a constrained photochemical box model ...
Atlas, E, Blake, D, Cantrell, C, Coffey, M, Eisele, F, Flocke, F, Fried, A, Heikes, B, Lefer, B, Madronich, S, Mauldin, L, Ridley, B, Shetter, R, Stroud, C, Talbot, R, Weinheimer, A, Wert, B   +16 more
core   +2 more sources

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Chemical synthesis and steady state characterization of a nanocrystalline lithium cobalt oxide

Universitas Scientiarum, 2020
Lithium cobalt oxide (LiCoO2 ) is one of the most relevant components in lithium-ion batteries. The array of sought-after features of LiCoO2 depends on its synthesis method.
Y. Neira-Guio, L.C. Canaria-Camargo2 , J.A. Gómez-Cuaspud, E. Vera-López
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Heterogeneous N2O5 Uptake During Winter: Aircraft Measurements During the 2015 WINTER Campaign and Critical Evaluation of Current Parameterizations [PDF]

, 2018
Nocturnal dinitrogen pentoxide (N2O5) heterogeneous chemistry impacts regional air quality and the distribution and lifetime of tropospheric oxidants.
Apel, Eric C., Campos, Teresa, Campuzano-Jost, Pedro, Cohen, Ronald C., Dibb, Jack E., Dube, William P., Ebben, Carly, Fibiger, Dorothy L., Guo, Hongyu, Hornbrook, Rebecca S., Jaegle, Lyatt, Jimenez, Jose L., Lee, Ben H., Lopez-Hilfiker, Felipe, McDuffie, Erin E., Reeves, J. Michael, Schroder, Jason C., Shah, Viral, Sparks, Tamara L., Thornton, Joel A., Veres, Patrick, Weber, Rodney J., Weinheimer, Andrew J., Wooldridge, Paul J.   +23 more
core   +2 more sources

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Computational study of ECN Spray A and Spray D combustion at different ambient temperature conditions

Transportation Engineering, 2020
The combustion process of the Engine Combustion Network (ECN) Spray A and Spray D is studied over a wide range of ambient temperatures from 750 K to 900 K.
J.M. García-Oliver, R. Novella, J.M. Pastor, L. Pachano   +3 more
doaj   +1 more source