Results 61 to 70 of about 539,119 (298)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Transcriptome free energy can serve as a dynamic patient-specific biomarker in acute myeloid leukemia

open access: yesnpj Systems Biology and Applications
Acute myeloid leukemia (AML) is prevalent in both adult and pediatric patients. Despite advances in patient categorization, the heterogeneity of AML remains a challenge.
Lisa Uechi   +10 more
doaj   +1 more source

Measurements of pernitric acid at the South Pole during ISCAT 2000 [PDF]

open access: yes, 2002
The first measurements of pernitric acid at the South Pole were performed during the second Investigation of Sulfur Chemistry in the Antarctic Troposphere (ISCAT 2000). Observed HO2NO2 concentrations averaged 25 pptv.
Buhr, Martin   +12 more
core   +2 more sources

Steady-State Distributions of O2 and OH in the High Atmosphere and Implications in the Ozone Chemistry [PDF]

open access: yesThe Journal of Physical Chemistry A, 2003
Although steady-state distributions are commonly accepted to be of the Boltzmann-type, such an assumption can be rather unrealistic when modeling the high atmosphere. Corroborating evidence is reported for the vibrationaland rotational distributions of O 2 and OH from detailed trajectory calculations, which shows that the thermalization assumption is ...
openaire   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Influence of Sea Ice‐Derived Halogens on Atmospheric HOx as Observed in Springtime Coastal Antarctica

open access: yesGeophysical Research Letters, 2019
We present first observations of OH and (HO2 + RO2) carried out in Antarctica outside the summer season. Measurements were made over 23 days in spring at the coastal Antarctic station Halley.
Neil Brough   +2 more
doaj   +1 more source

Self-propulsion of a catalytically active particle near a planar wall: from reflection to sliding and hovering

open access: yes, 2015
Micron-sized particles moving through solution in response to self-generated chemical gradients serve as model systems for studying active matter. Their far-reaching potential applications will require the particles to sense and respond to their local ...
Dietrich, S.   +3 more
core   +1 more source

Photochemistry in the arctic free troposphere: NOx budget and the role of odd nitrogen reservoir recycling [PDF]

open access: yes, 2003
The budget of nitrogen oxides (NOx) in the arctic free troposphere is calculated with a constrained photochemical box model using aircraft observations from the Tropospheric O3 Production about the Spring Equinox (TOPSE) campaign between February and May.
Atlas, E   +13 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Toric dynamical systems [PDF]

open access: yes, 2007
Toric dynamical systems are known as complex balancing mass action systems in the mathematical chemistry literature, where many of their remarkable properties have been established.
Craciun, Gheorghe   +3 more
core  

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