Multiple Transients in the Pre-Steady-State of Nucleoside Hydrolase Reveal Complex Substrate Binding, Product Base Release, and Two Apparent Rates of Chemistry [PDF]
Biochemistry, 2006 We have investigated the transient kinetics of the nucleoside hydrolase from Trypanosoma vivax (TvNH) at low temperatures (5 degrees C). Three novel absorbance transients (termed tau1, tau3, and tau4) were detected during multiple-guanosine turnover stopped-flow absorbance spectroscopy, in addition to a transient (tau2) that had been observed ...
Vandemeulebroucke, An +3 more
openaire +3 more sources
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Cryo-EM structure of respiratory complex I at work
eLife, 2018 Mitochondrial complex I has a key role in cellular energy metabolism, generating a major portion of the proton motive force that drives aerobic ATP synthesis.
Kristian Parey +7 more
doaj +1 more source
Hydroxyl radical in/on illuminated polar snow: formation rates, lifetimes, and steady-state concentrations [PDF]
Atmospheric Chemistry and Physics, 2016 While the hydroxyl radical (•OH) in the snowpack is likely a dominant oxidant for organic species and bromide, little is known about the kinetics or steady-state concentrations of •OH on/in snow and ice.
Z. Chen +5 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
On the chemistry of hydrides of N atoms and O$^+$ ions [PDF]
, 2016 Previous work by various authors has suggested that the detection by Herschel/HIFI of nitrogen hydrides along the low density lines of sight towards G10.6-0.4 (W31C) cannot be accounted for by gas-phase chemical models.
Awad, Zainab +2 more
core +2 more sources
Critical Loads of Acid Deposition for Wilderness Lakes in the Sierra Nevada (California) Estimated by the Steady-State Water Chemistry Model [PDF]
Water, Air, & Soil Pollution, 2013 Major ion chemistry (2000–2009) from 208 lakes (342 sample dates and 600 samples) in class I and II wilderness areas of the Sierra Nevada was used in the Steady-State Water Chemistry (SSWC) model to estimate critical loads for acid deposition and investigate the current vulnerability of high elevation lakes to acid deposition. The majority of the lakes
Shaw, Glenn D +4 more
openaire +3 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Observations of total peroxy nitrates and aldehydes: measurement interpretation and inference of OH radical concentrations [PDF]
Atmospheric Chemistry and Physics, 2007 We describe measurements of total peroxy nitrates (ΣPNs), NO2, O3 and several aldehydes at Granite Bay, California, during the Chemistry and Transport of the Sacramento Urban Plume-2001 (CATSUP 2001) campaign, from 19 July–16 September 2001 ...
P. A. Cleary +10 more
doaj
Fluctuation corrections on thermodynamic functions: Finite size effect
, 2013 The explicit thermodynamic functions, in particular, the specific heat of a spin system interacting with a spin bath which exerts finite dissipation on the system are determined.
Ghosh, Arnab +2 more
core +1 more source