Results 111 to 120 of about 125,716 (297)

Viability assessment and transplantation of fatty liver grafts using end‐ischemic normothermic machine perfusion

open access: yesLiver Transplantation, EarlyView., 2022
Abstract End‐ischemic viability testing by normothermic machine perfusion (NMP) represents an effective strategy to recover liver grafts having initially been discarded for liver transplantation (LT). However, its results in the setting of significant (≥30%) macrovesicular steatosis (MaS) have not been specifically assessed.
Damiano Patrono   +8 more
wiley   +1 more source

Indole-3-propionic acid inhibits gut dysbiosis and endotoxin leakage to attenuate steatohepatitis in rats

open access: yesExperimental and Molecular Medicine, 2019
Microbial metabolites have emerged as critical components that mediate the metabolic effects of the gut microbiota. Here, we show that indole-3-propionic acid (IPA), a tryptophan metabolite produced by gut bacteria, is a potent anti-non-alcoholic ...
Ze-Hua Zhao   +14 more
semanticscholar   +1 more source

Valorization of the peel and husk of guaraná (Paullinia cupana): oil extraction, chemical composition, cytotoxicity, and antitumor potential

open access: yesBiofuels, Bioproducts and Biorefining, EarlyView.
Abstract Guaraná (Paullinia cupana) is a fruit native to the Amazon region. Due to its widespread use, primarily in beverages, its production has grown over the years. The seed is the only commercially valuable part of the fruit so the guaraná production chain generates byproducts, including peel, husk, and spent seed.
Leiliane do Socorro Sodré de Souza   +9 more
wiley   +1 more source

An open-label randomized control study to compare the efficacy of vitamin e versus ursodeoxycholic acid in nondiabetic and noncirrhotic Indian NAFLD patients

open access: yesThe Saudi Journal of Gastroenterology, 2016
Background/Aim: The study was carried out to compare the efficacy of Vitamin E versus Ursodeoxycholic acid (UDCA) in nondiabetic nonalcoholic fatty liver disease (NAFLD) patients.
Pathik Parikh   +5 more
doaj   +1 more source

Quantitative Systems Toxicology Modeling with DILIsym to Support Phase 3 Dose Selection for Fezolinetant

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Fezolinetant is a first‐in‐class, selective, non‐hormonal, neurokinin 3 receptor antagonist that is approved for the treatment of moderate to severe vasomotor symptoms due to menopause. In a phase 2b clinical study (n = 352), nine study participants experienced elevations in serum transaminases exceeding three times the upper limit of normal.
Jace C. Nielsen   +11 more
wiley   +1 more source

Корекція ендотоксикозу і синдрому пероксидації у хворих на подагру в поєднанні з неалкогольним стеатогепатитом = Lipid peroxidation and endotoxemia syndrome сorrection in patients with gout combined with nonalcoholic steatohepatitis

open access: yesJournal of Education, Health and Sport, 2015
Smiyan S. I., Danchak S. V. Корекція ендотоксикозу і синдрому пероксидації у хворих на подагру в поєднанні з неалкогольним стеатогепатитом = Lipid peroxidation and endotoxemia syndrome сorrection in patients with gout combined with nonalcoholic ...
S. I. Smiyan, S. V. Danchak
doaj  

The clinician's view on the advantages and contradictions of the new nomenclature of steatotic liver disease: A review

open access: yesТерапевтический архив
In September 2023, the European Association for the Study of the Liver (EASL) updated the disease nomenclature for non-alcoholic (metabolically associated) fatty liver disease.
Chavdar S. Pavlov   +9 more
doaj   +1 more source

Hepatic Deficiency of Augmenter of Liver Regeneration Predisposes to Nonalcoholic Steatohepatitis and Fibrosis

open access: green, 2020
Sudhir Kumar   +9 more
openalex   +2 more sources

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