Gender Differences in Bile Acids and Microbiota in Relationship with Gender Dissimilarity in Steatosis Induced by Diet and FXR Inactivation. [PDF]
, 2017 This study aims to uncover how specific bacteria and bile acids (BAs) contribute to steatosis induced by diet and farnesoid X receptor (FXR) deficiency in both genders.
French, Samuel W +8 more
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Advanced Science, EarlyView.This report describes a nano magnesium nourisher, named MgC@PS, capable of targeted Mg2⁺ delivery to macrophages, effectively suppressing The nuclear factor kappa B (NF‐κB) activation and mitigating NLRP3 inflammasome‐driven pyroptosis in liver inflammation.
Li Wang +13 more
wiley +1 more source
FibroScan-AST (FAST) score for the non-invasive identification of patients with non-alcoholic steatohepatitis with significant activity and fibrosis: a prospective derivation and global validation study [PDF]
, 2020 Philip N. Newsome +22 more
openalex +1 more source
Comparison of magnetic resonance spectroscopy, proton density fat fraction and histological analysis in the quantification of liver steatosis in children and adolescents [PDF]
, 2016 AIM: To establish a threshold value for liver fat content between healthy children and those with non-alcoholic fatty liver disease (NAFLD) by using magnetic resonance imaging (MRI), with liver biopsy serving as a reference standard.
BEZZI, Mario +6 more
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Advanced Science, EarlyView.ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang +8 more
wiley +1 more source
СКРИНИНГОВЫЕ МЕТОДЫ ВЫЯВЛЕНИЯ ФИБРОЗА ПЕЧЕНИ
Архивъ внутренней медицины, 2012 The article presents current data on the diagnosis methods of liver diseases. Recommendations on the management of patients with pathology of the hepatic system on the detection of disease are given.
С. С. Вялов
doaj +1 more source
Novel Molecular Mechanisms in the Development of Non-Alcoholic Steatohepatitis. [PDF]
, 2016 Non-alcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease in adults and children worldwide. NAFLD has become a severe health issue and it can progress towards a more severe form of the disease, the non-alcoholic ...
Feldstein, Ariel E, Povero, Davide
core +2 more sources
Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases
Advanced Science, EarlyView.Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu +9 more
wiley +1 more source
The Saudi Journal of Gastroenterology, 2016 Background/Aim: The study was carried out to compare the efficacy of Vitamin E versus Ursodeoxycholic acid (UDCA) in nondiabetic nonalcoholic fatty liver disease (NAFLD) patients.
Pathik Parikh +5 more
doaj +1 more source
Vitamin D to reduce liver fibrosis in non-alcoholic fatty liver disease [PDF]
, 2017 BACKGROUND: As the prevalence of metabolic risk factors in the American population has increased over time, so too has the diagnoses of non-alcoholic fatty liver disease (NAFLD).
Fox, Ryan
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