Results 241 to 250 of about 170,525 (342)

Chronic-plus-binge alcohol intake induces production of proinflammatory mtDNA-enriched extracellular vesicles and steatohepatitis via ASK1/p38MAPKα-dependent mechanisms. [PDF]

JCI Insight
Ma J, Cao H, Rodrigues RM, Xu M, Ren T, He Y, Hwang S, Feng D, Ren R, Yang P, Liangpunsakul S, Sun J, Gao B.   +12 more
europepmc   +1 more source

Harnessing Gut Microbiome–Brain–Liver Crosstalk: Novel Therapeutic Strategies for Metabolic Dysfunction‐Associated Steatotic Liver Disease

Medicine Bulletin, EarlyView.
This review reveals the complex mechanisms by which the brain–gut–liver axis (particularly the gut microbiota and its metabolites) drives MASLD, highlighting the therapeutic value of using phages to target and eliminate pathogenic bacteria and their metabolic products.
Xingtao Zhao, Ruolan Li, Jingdong Zhao, Ruiqi Sun, Shuo Zhang, Qiong Pan, Hongyan Lu, Jin Chai   +7 more
wiley   +1 more source

Correction: Steatosis is involved in the progression of kidney disease in a high-fat-diet-induced non-alcoholic steatohepatitis mouse model. [PDF]

PLoS One
PLOS One Staff.
europepmc   +1 more source

Nonalcoholic fatty liver, steatohepatitis, and the metabolic syndrome

Hepatology, 2003
G. Marchesini, E. Bugianesi, G. Forlani, F. Cerrelli, M. Lenzi, R. Manini, S. Natale, E. Vanni, N. Villanova, N. Melchionda, M. Rizzetto   +10 more
semanticscholar   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Disparities in liver transplantation for metabolic dysfunction-associated steatohepatitis-associated hepatocellular carcinoma. [PDF]

World J Transplant
Victor DW, Kodali S, Noureddin M, Brombosz EW, Lopez A, Basra T, Graviss EA, Nguyen DT, Saharia A, Connor AA, Abdelrahim M, Cheah YL, Simon CJ, Hobeika MJ, Mobley CM, Ghobrial RM.   +15 more
europepmc   +1 more source

An Integrated Engineering Approach to Creating Health‐Modulating Postbiotics

Molecular Nutrition &Food Research, EarlyView.
Postbiotics have emerged as a promising alternative to live probiotics, offering comparable health benefits while overcoming challenges related to safety, stability, and shelf life. The review addresses current challenges in standardizing postbiotic definitions and production processes, and by outlining future research directions necessary to unlock ...
Michael Leonidas Chikindas, Diana E. Roopchand, Santosh Kumar Tiwari, Liubov S. Sichel, Mukund V. Karwe, Nitin Nitin, Vitor Luis Fagundes, Igor V. Popov, John R. Tagg, Xuanxuan Lu, Svetoslav Dimitrov Todorov   +10 more
wiley   +1 more source

Burden and trends of nonalcoholic steatohepatitis-related liver cancer in China: A population-based observational study using GBD 2021 data. [PDF]

Medicine (Baltimore)
Xiang MX, Yan P, Lan B, Deng JB, Tan J.
europepmc   +1 more source

Supervised learning reveals circulating biomarker levels diagnostic of hepatocellular carcinoma in a clinically relevant model of non-alcoholic steatohepatitis; An OAD to NASH

, 2018
Anne Hwang, Christopher Shi, Edward Y. Zhu, Farha Naaz, Ping Zhou, Zainab Rasheed, Xiaoqing Liu, Lindsey Jung, Bin Duan, Jingsong Li, Kai Jiang, Latha Paka, Satishkumar Gadhiya, Dibyendu Dana, Quaisar Ali, Michael Yamin, Itzhak D. Goldberg, Prakash Narayan   +17 more
openalex   +2 more sources

Nonalcoholic Steatohepatitis Is the Fastest Growing Cause of Hepatocellular Carcinoma in Liver Transplant Candidates

Clinical Gastroenterology and Hepatology, 2019
Z. Younossi, M. Stepanova, J. Ong, I. Jacobson, E. Bugianesi, A. Duseja, Yuichiro Eguchi, V. Wong, F. Negro, Y. Yılmaz, M. Romero‐Gomez, J. George, Aijaz Ahmed, R. Wong, I. Younossi, M. Ziayee, A. Afendy   +16 more
semanticscholar   +1 more source