Results 281 to 290 of about 170,525 (342)

Effects of Resmetirom on Metabolic‐Dysfunction Associated Steatohepatitis in Patients With Weight Loss and/or Diabetes Taking Glucagon‐Like Peptide‐1 Receptor Agonists and Other Diabetes Therapies: A Secondary Analysis of the MAESTRO‐NASH Trial

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
This secondary analysis of the MAESTRO‐NASH trial examined the effects of resmetirom in patients with weight loss and/or treated with therapies for T2D. The efficacy of resmetirom was not impacted by background T2DM therapies. Weight loss (≥ 5%) enhanced the effect of resmetirom on multiple MASH endpoints. ABSTRACT Background MAESTRO‐NASH, a randomised,
Mazen Noureddin   +7 more
wiley   +1 more source

CD44 in Group 1 Innate Lymphoid Cells Impacts the Development and Progression of Steatohepatitis. [PDF]

open access: yesLiver Int
Bourinet M   +20 more
europepmc   +1 more source

Prevalence of nonalcoholic fatty liver disease and nonalcoholic steatohepatitis among a largely middle-aged population utilizing ultrasound and liver biopsy: a prospective study.

open access: yesGastroenterology, 2011
C. D. Williams   +7 more
semanticscholar   +1 more source

Alterations in Gut Microbiota and Metabolism in Cirrhotic Portal Hypertension: Implications for Disease Progression

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
In‐depth multiomics analyses revealed that the gut microbiota in patients with CPH is dysbiotic. Altered gut microbiota plays an important role in the progression of CPH and affects the host's arginine metabolism to promote arginine biosynthesis. The pro‐inflammatory effects of certain gut bacteria induce iNOS expression, which together act on the ...
Qun Zhang   +15 more
wiley   +1 more source

Research Communication: Changing Aetiology of Chronic Liver Diseases in East Asia Pacific and HCC Surveillance in Non‐Cirrhotic Patients

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
East Asia Pacific faces a rising CLD burden, with MASLD projected to account for 80% of CLD prevalence by 2040. HCC surveillance in non‐cirrhotic patients is cost‐effective only in select older age groups. Wide variation in thresholds across countries highlights the need for updated guidelines and risk‐based surveillance strategies.
Ming Liu   +4 more
wiley   +1 more source

Is there a role for cannabidiol in obesity, metabolic syndrome and binge eating?

open access: yesBritish Journal of Pharmacology, EarlyView.
Cannabidiol (CBD) is one of the most abundant phytocannabinoids isolated from the Cannabis sativa plant. CBD is a lipophilic, non‐intoxicating substance that differently from Δ9‐tetrahydrocannabinol (Δ9‐THC) does not present the typical profile of a drug of abuse.
Luca Botticelli   +7 more
wiley   +1 more source

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