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Bile Acid Binding Resins Improve Glucagon Receptor Agonist‐Mediated Weight Loss in Diet‐Induced Obese Mice

open access: yesObesity, EarlyView.
ABSTRACT Objective Glucagon‐receptor (GCGR) agonism reguglates bile acid (BA) metabolism and promotes weight loss in diet‐induced obese (DIO) mice. Thus, we hypothesized that BA signaling contributes to GCGR‐stimulated weight loss. Methods To test this hypothesis, we utilized BA‐binding resins (BARs; colesevelam [Colsv] and cholestyramine [Cstyr]) to ...
Teayoun Kim   +9 more
wiley   +1 more source

Metabolic-Associated Steatotic Liver Disease and FGF21 Dysregulation in Seipin-Deficient and <i>BSCL2</i>-Associated Celia's Encephalopathy Murine Models. [PDF]

open access: yesInt J Mol Sci
Cobelo-Gómez S   +9 more
europepmc   +1 more source

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