Results 311 to 320 of about 236,526 (353)

Classification of Nonalcoholic Fatty Liver Grades using Pre-Trained Convolutional Neural Networks and a Random Forest Classifier on B-Mode Ultrasound Images. [PDF]

J Biomed Phys Eng
Naderi Yaghouti AR, Shalbaf A.
europepmc   +1 more source

Human Cyclophilins—An Emerging Class of Drug Targets

Medicinal Research Reviews, EarlyView.
ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova, Hana Navratilova, Kamil Musilek, Ondrej Benek   +3 more
wiley   +1 more source

Age- and Sex-dependent Effects of High-fructose, High-fat Diets on Small Bowel Inflammation and Hepatic Steatosis in F344 Rats. [PDF]

J Neurogastroenterol Motil
Ha S, Kim N, Choi SI, Nam RH, Jang JY, Kim EH, Song CH, Na HY, Kim W.   +8 more
europepmc   +1 more source

Protective Roles of Prebiotics and Probiotics Against Environmental Pollutant‐Induced Toxicities: A Systematic Review of Animal Studies

Molecular Nutrition &Food Research, EarlyView.
Pollutant‐induced epithelial damage also leads to a cascade of harmful effects, including reduced mucus secretion, decreased luminal pH, and enhanced absorption of toxins. These changes contribute to oxidative stress (↑ malondialdehyde (MDA); ↓ superoxide dismutase (SOD), catalase (CAT), glutathione (GSH), glutathione peroxidase (GPx), and heightened ...
Meysam Zarezadeh Ph.D., Ahmad Saedisomeolia, Mahsa Mahmoudinezhad, Michele M. Iskandar, Fang Lu, Stan Kubow   +5 more
wiley   +1 more source

Screening for metabolic-associated fatty liver disease in type 2 diabetes patients using non-invasive scores and ultrasound: a cross-sectional study in Egypt. [PDF]

BMC Gastroenterol
Semeya AA, Hafez RSAA, Ewais SHM, Mostafa SM, Eldeeb A, Elgamal R, Othman AAA.   +6 more
europepmc   +1 more source

AMPK‐Dependent Epigenetic Regulation of Metabolism Mediates the Anti‐Cancer Action of Pterostilbene in Hepatocellular Carcinoma

Molecular Nutrition &Food Research, EarlyView.
This study investigates the anti‐cancer effects of pterostilbene (PTS), a naturally occurring dietary phytoestrogen, in a rat model of hepatocellular carcinoma (HCC) induced by a choline‐deficient L‐amino acid‐defined (CDAA) diet. Supplementation with PTS significantly reduces liver steatosis and tumor formation.
Cayla Boycott, Megan Beetch, Katarzyna Lubecka‐Gajewska, Benjamin S. Ramsey, Sandra Torregrosa‐Allen, Bennett D. Elzey, Abigail Cox, Nadia Atallah Lanman, Aline de Conti, Min Li, Mario Ferruzzi, Igor Pogribny, Barbara Stefanska   +12 more
wiley   +1 more source

From steatosis to cirrhosis: the role of obesity in the progression of liver disease. [PDF]

J Diabetes Metab Disord
Nowak K, Paluch M, Cudzik M, Syska K, Gawlikowska W, Janczura J.   +5 more
europepmc   +1 more source

High‐Fat Diet–Wheat Gluten Interactions in HLA‐DQ8 Transgenic Mice

Molecular Nutrition &Food Research, EarlyView.
This study shows how eating a high‐fat diet (HFD) and gluten together influences inflammation, energy balance, and immune responses in HLA‐DQ8 transgenic (DQ8 tg) mice. These findings may provide new insights into how specific dietary components interact to impact metabolic and immune‐related disorders.
Yuri Haneishi, Lucia Treppiccione, Vera Rotondi Aufiero, Francesco Maurano, Saya Watanabe, Diomira Luongo, Giuseppe Mazzarella, Junki Miyamoto, Mauro Rossi   +8 more
wiley   +1 more source

Role of Vitamin D Supplementation in Chronic Liver Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. [PDF]

Nutr Rev
Martinekova P, Obeidat M, Topala M, Váncsa S, Veres DS, Zolcsák Á, Pál M, Földvári-Nagy L, Banovcin P, Erőss B, Hegyi P, Hagymasi K.   +11 more
europepmc   +1 more source

The Impact of Antidiabetic Therapy on Liver Injury, Steatosis, and Fibrosis in Patients with Type 2 Diabetes and Metabolic Dysfunction-Associated Steatotic Liver Disease. [PDF]

Medicina (Kaunas)
Albai O, Braha A, Timar R, Lazăr S, Popescu S, Timar B.   +5 more
europepmc   +1 more source