Results 31 to 40 of about 26,101 (265)

Performance of Steel Fiber-Reinforced Concrete Pier under Impact Load

open access: yesAdvances in Civil Engineering, 2022
Vehicular impact on bridge piers is one of the leading causes of bridge failure. Due to the increase in vehicle-pier collisions, many researchers have studied the performance of RC bridge piers under vehicle collisions.
Melaknesh Dessalegn, Temesgen Wondimu
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Fire behavior of composite steel truss bridge girders: numerical investigation and design strategies

open access: yesAdvances in Bridge Engineering
Fire pose more severe threat to steel truss bridge girders as compared to common steel plate and box bridge girders. To deeply clarify failure mechanism of fire exposed steel truss bridge girders, this paper presents an investigation on fire performance ...
Gang Zhang   +5 more
doaj   +1 more source

Corrosion Fatigue Assessment of Bridge Cables Based on Equivalent Initial Flaw Size Model

open access: yesApplied Sciences, 2023
Bridge cables under traffic loads are more prone to failure during the service life due to the corrosion–fatigue coupling effect. In this study, a novel lifespan model based on the equivalent initial flaw size (EIFS) theory is established to analyze the ...
Zhongxiang Liu   +4 more
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

open access: yesFEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang   +6 more
wiley   +1 more source

Feasibility and Tolerability of Performing Portable MRI for Neurological Disorders in an Outpatient Neurology Clinic: A Prospective Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Accessing brain magnetic resonance imaging (MRI) can be challenging, especially for underserved patients, which may lead to disparities in neurological diagnosis. Method This mixed‐methods study enrolled adults with one of four neurological disorders: mild cognitive impairment or dementia of the Alzheimer type, multiple sclerosis ...
Maya L. Mastick   +19 more
wiley   +1 more source

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec   +6 more
wiley   +1 more source

Integrated Design of Structure and Material of Epoxy Asphalt Mixture Used in Steel Bridge Deck Pavement

open access: yesBuildings, 2021
To comprehensively investigate the integrated structural and material design of the epoxy asphalt mixture used in steel bridge deck pavement, the following works have been conducted: 1.
Wen Nie   +4 more
doaj   +1 more source

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