Results 41 to 50 of about 433,351 (312)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Corrosion Fatigue Assessment of Bridge Cables Based on Equivalent Initial Flaw Size Model
Applied Sciences, 2023 Bridge cables under traffic loads are more prone to failure during the service life due to the corrosion–fatigue coupling effect. In this study, a novel lifespan model based on the equivalent initial flaw size (EIFS) theory is established to analyze the ...
Zhongxiang Liu +4 more
doaj +1 more source
Vulnerability assessment of the S. João de Loure Bridge: Vouga’s river [PDF]
, 2005 Steel bridges are particularly sensible to corrosion, which can put at risk the structural safety by affecting the joint elements. Having this in mind, the objective of this work was to evaluate the influence of the joint's stiffness in the structural ...
Fernandes, C., Varum, H.
core +1 more source
Analysis of an Orthotropic Deck Stiffened with a Cement-Based Overlay [PDF]
, 2007 Over the past years, with increasing traffic volumes and higher wheel loads, fatigue damage in steel parts of typical orthotropic steel bridge decks, has been experienced on heavily trafficked routes.
Olesen, John Forbes +3 more
core +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Structural health monitoring and bridge condition assessment [PDF]
, 2016 Thesis (Ph.D.) University of Alaska Fairbanks, 2016This research is mainly in the field of structural identification and model calibration, optimal sensor placement, and structural health monitoring application for large-scale structures.
Xiao, Feng, 肖枫
core
Bumpers for reducing the effect of pounding between bridge decks [PDF]
, 2004 The study addresses the influence of bumpers as reduction measures at the bridge decks. The considered devices are steel spring, steel spring with additional viscous damper or steel spring with additional friction element.
Chouw, Nawawi, Su, Hai, Taniguchi, Takeo
core +1 more source
CX3CL1 in Early Detection of Alzheimer's Disease: Plasma Dynamics Across Age and Disease Stages
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Backgrounds Alzheimer's disease (AD) is characterized by amyloid‐beta plaques, tau tangles, and neuroinflammation. C‐X3‐C motif chemokine ligand 1 (CX3CL1, also known as fractalkine), a neuroimmune chemokine implicated in AD pathogenesis, shows inconsistent alterations in plasma/serum across studies.
Ling Wang +6 more
wiley +1 more source
Buildings, 2021 To comprehensively investigate the integrated structural and material design of the epoxy asphalt mixture used in steel bridge deck pavement, the following works have been conducted: 1.
Wen Nie +4 more
doaj +1 more source
Automated Pin-Dot Marking Effects on A709-Gr50 Steel Plate Fatigue Capacity [PDF]
, 2017 During fabrication of multi-piece steel bridge assemblies, markings are often made on the steel surface to identify/track individual pieces or to provide reference for fabrication layout or later erection.
Noernberg, Michael Andrew
core +2 more sources