Results 141 to 150 of about 1,600 (175)

Decoding RNA regulation: Challenges and opportunities for RNA‐based therapies in Europe

British Journal of Clinical Pharmacology, EarlyView.
Abstract RNA‐based medicinal products represent a promising frontier in personalised medicine, offering sequence‐specific disease targeting at various molecular levels, yet their clinical translation in the European Union (EU) may be hindered by regulatory uncertainty around definitions and evidence requirements; this study therefore aims to identify ...
Olivia C. Lewis, Christine Leopold, Joyce M. Hoek, Raymond M. Schiffelers, Marie L. De Bruin   +4 more
wiley   +1 more source

Conveyor belt restraining in natural hazardous wind events. [PDF]

Sci Rep
Golovanevskiy V, Kondratiev A.
europepmc   +1 more source

More‐than‐gender? Moving beyond gendered expectations of divergent learners in early childhood education

British Educational Research Journal, EarlyView.
Abstract In this paper, we explore how neurodivergent ways of being in early education are often gendered. The intersectionalities of gender and neurodivergence often lead to fixed expectations that perpetuate binary interpretations, pathologisations, missed diagnoses and a lack of curated support.
Ruth Churchill Dower, Hannah Hogarth
wiley   +1 more source

Experimental and numerical study on the mechanical properties of F type socket joints for rectangular pipe jacking with steel screw connection. [PDF]

Sci Rep
Xu Y, Xu C, Zhang C, Zhang X.
europepmc   +1 more source

Enhancing the Secretion Systems: Genetic Engineering of Super Bioagents for Effective Plant Disease Control

Biotechnology and Bioengineering, EarlyView.
Genetic engineering (GE) overcomes BCA limits, enabling robust, scalable crop protection. “Super Bioagents” (SBs) use optimized SSs to enhance bioactive molecule delivery. Optimizing SSs enhance precise, sustainable effector deployment for stable disease suppression. SBs use microbiome‐informed design for scalable, next‐gen sustainable crop protection.
Michael Dare Asemoloye
wiley   +1 more source

An Experimental Investigation of Twelve Concrete Beams Post-Tensioned with Unbonded Tendons Under Center-Point and Third-Point Loading. [PDF]

Materials (Basel)
Politalski W, Seruga A.
europepmc   +1 more source

Overcoming intranasal delivery barriers with ultrastable polyzwitterionic siRNA nanocages for enhanced glioblastoma therapy

BMEMat, EarlyView.
A ROS‐responsive, zwitterionic nanocage enables stable, intranasal siRNA delivery to glioblastoma, promoting deep tumor penetration via non‐degradative pathways and trigeminal nerve transport. This platform achieves durable gene silencing and tumor suppression, offering a non‐invasive, storage‐stable strategy for treating glioma and other neurological ...
Jingwen Xie, Jingxing Si, Xiaobei Deng, Jing Tan, Ruijie Zhu, Jizhou Qi, Gaoxia Ma, Bin Wang, Yi Wang, Yunzhou Guo, Yuping Chen, Shiqun Shao, Youqing Shen   +12 more
wiley   +1 more source

Effect of Low Corrosion Levels on the Bond Performance of Lap-Splices in Reinforced Concrete Beams. [PDF]

Materials (Basel)
Gillani ASM, Yi C, Hong KJ.
europepmc   +1 more source

Enhancing punching shear and post-punching behavior of flat slabs using wire mesh, integrity bars and fibers. [PDF]

Sci Rep
Janabi A, Esfahani MR.
europepmc   +1 more source

Incorporation of Nitinol (NiTi) Shape Memory Alloy (SMA) in Concrete: A Review. [PDF]

Materials (Basel)
Turkmen M, Issa A, Awayssa O, El-Hassan H.   +3 more
europepmc   +1 more source