Results 31 to 40 of about 596,686 (360)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Numerical modelling of the effect of using multi-explosives on the explosive forming of steel cones [PDF]

, 2016
Modelling and analysis of underwater explosive forming process by using FEM and SPH formulation is presented in this work. The explosive forming of a steel cone is studied.
Campbell, JC, De Vuyst, T, Djordjevic, N, Hughes, K, Kong, K, Vignjevic, R   +5 more
core   +1 more source

One size does not fit all: An in vitro evaluation of the effects of bezafibrate and medroxyprogesterone acetate on human SH‐SY5Y and U‐87 MG cancer cells

FEBS Open Bio, EarlyView.
Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar, Francesco Michelangeli, Farhat Latif Khanim, Christopher Martin Bunce, William Eustace Basil Johnson   +4 more
wiley   +1 more source

Warm rolling combined with rare earth yttrium segregation induces secondary recrystallization in strip-cast Fe-3%Si grain-oriented silicon steel

Materials Research Express
The effect of warm-rolling on the microstructure, texture, and magnetic properties of ultra-low carbon yttrium (Y) -doped grain-oriented (Y-GO) Fe-3%Si steel as-cast strips were systematically investigated.
Shun Wang, Weixue Dou, Hongguo Wang, Li Xie, Shuo Yang, Tiannan Zhu, Yang Tang, Guo Yuan   +7 more
doaj   +1 more source

Inuence of Foam Filling on Dynamic Response of Hemispherical Shell Subjected to Blast Pressure. [PDF]

, 2013
The paper aims to investigate the effect of aluminium foam filling of hemispherical steel shell on its dynamic response, accounting for the blast pressure modelling. The considered structures subjected to uniformly distributed pressure, rigidly connected
Kowal-Michalska, Katarzyna, Niezgodziński, Tadeusz, Świniarski, Jacek   +2 more
core  

Clinical Validation of Plasma p‐217tau in Neurological Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma p‐217tau is a minimally invasive but specific biomarker for diagnosing Alzheimer's disease (AD). However, its disease specificity remains to be clinically evaluated. We validated the reliability of the p‐217tau biomarker in 12 other neurological diseases.
Takeshi Kawarabayashi, Takumi Nakamura, Ryoma Takahashi, Tetsuya Ueda, Seiji Kinoshita, Chikage Uchida, Takashi Sugawara, Kentaro Hashimoto, Kunihiko Ishizawa, Masakuni Amari, Hiroo Kasahara, Yoshio Ikeda, Masamitsu Takatama, Mikio Shoji   +13 more
wiley   +1 more source

Laboratory Study on Oxide Inclusions in High-Strength Low-Alloyed Steel Refined by Slag with Basicity 2–5

High Temperature Materials and Processes, 2015
Non-metallic inclusions in high-strength low-alloyed steel refined by slag with basicity (B) 2–5 and Al2O3 content 20%–30% (in mass percent) were investigated by slag–metal equilibrium experiments in laboratory and thermodynamic calculations.
Yu Huixiang, Wang Xinhua, Zhang Jing, Wang Wanjun   +3 more
doaj   +1 more source

A study on levitation performance improvement of bent flexible steel plate

Mechanical Engineering Journal, 2018
Levitation improvement of the bending levitation performance of thin steel plate was performed. First, the point of the steel plate where the vibration is predominantly generated was estimated using an ultrathin steel plate with a thickness of 0.18 mm ...
Hideaki KATO, Kazuki OGAWA, Makoto TADA, Yoshiho ODA, Xiaojun LIU, Ayato ENDO, Keigo IKEDA, Takayoshi NARITA   +7 more
doaj   +1 more source

Lightweight universal joint transmits both torque and thrust [PDF]

, 1964
A lightweight universal joint uses a thin steel flexure plate to transmit torque and a steel rod to transmit thrust.
Bamford, R. M.
core   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento, Daniela F. Santos, Tuane C. R. G. Vieira, Tiago F. Outeiro   +3 more
wiley   +1 more source