Results 51 to 60 of about 879,092 (307)

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

Analysis of the therapeutic effect of artificial leather embedding combined with fascial sleeve flap transplantation on chronic wounds of lower limbs with bone and plate exposure

BMC Surgery, 2022
Background After severe trauma of lower limbs, bone, tendon or plate graft exposure is common. The traditional repair method is to use a variety of skin flap transplantation to cover the exposed part, but the wound often can not heal after operation, or ...
Yong Li, Zhi-bo Zhang, Ji-song Liu, Zhu-min Wu, Xin-cheng Sun, Yu-tin Zhao, Xiang-zhou Zhang   +6 more
doaj   +1 more source

Co‐Delivery of Sustained Release Chondroitinase ABC‐37 With Human iPSC‐Derived Neural Progenitors Promotes Transplant Survival and Functional Recovery in a Rodent Model of Stroke

Advanced Science, EarlyView.
A regenerative strategy for stroke combines human stem cell–derived neural progenitor cells with sustained release of a matrix‐modifying, thermostable chondroitinase ABC‐37 enzyme. In a rat model of stroke, co‐delivery enhanced transplanted cell survival and neuronal differentiation, degraded inhibitory extracellular matrix components, and improved ...
Nitzan Letko Khait, David Xinzheyang Li, Keyi Guo, Hong Cui, Quinton Sirianni, Dhana Abdo, Cindi M. Morshead, Molly S. Shoichet   +7 more
wiley   +1 more source

New device for saphenous vein-to-aorta proximal anastomosis without side-clamping

Journal of Cardiothoracic Surgery, 2007
Background Side clamping to perform saphenous vein-to-aorta proximal anastomosis is a well known cause of cerebral embolization during coronary bypass surgery.
Tappainer Ernesto
doaj   +1 more source

VDAC1 Upregulation Induces Hyperexcitability of Nociceptive Sensory Neurons Via Enhanced Mitochondrial Atp Efflux in Neuropathic Pain

Advanced Science, EarlyView.
The mechanism diagram of VDAC1 mediating neuronal excitability and neuropathic pain. Briefly, VDAC1 is expressed in DRG neurons and is upregulated following CCI‐induced neuropathic pain. This upregulation enhances ATP transport from mitochondria to the cytoplasm in sensory neurons, leading to increased neuronal excitability and pain behavior.
Fengrun Sun, Ning Yu, Liang Yu, Xiaofen Tian, Yujia Ma, Yikuan Xie, Tao Wang, Chao Ma   +7 more
wiley   +1 more source

Effectiveness of Palatopharyngeal Surgery Modifications in Obstructive Sleep Apnea: A Meta‐analysis

OTO Open
Objective The effectiveness of various palatopharyngeal surgeries is currently poorly understood. This study compares various palatopharyngeal surgery techniques without tonsillectomy for reducing the apnea‐hypopnea index (AHI).
Samuel Tschopp, Flora Meinert, Georgios Mantokoudis, Marco Caversaccio, Urs Borner   +4 more
doaj   +1 more source

Repair Integrity and Re-tear Pattern after Arthroscopic Suture-Bridge Rotator Cuff Repair Abbreviating Medial-row Knot-tying

Orthopaedic Journal of Sports Medicine, 2019
Objectives: Recently suture bridging technique has become the most popular footprint reconstruction procedure, and many surgeons prefer to perform lateral row fixation after tying the medial-row suture.
Yasutaka Takeuchi MD, Hiroyuki Sugaya MD, Norimasa Takahashi MD, Keisuke Matsuki M.D., Ph.D., Morihito Tokai MD, Takeshi Morioka, Yusuke Ueda MD, Hiroshige Hamada   +7 more
doaj   +1 more source

Effect of steel wire sutures on the incidence of chemically induced rodent colonic tumours

Journal of British Surgery, 1986
Abstract An experiment is presented which shows that colonic primary tumours cluster around a previously constructed anastomosis and that the choice of suture materials (but not the technique of their insertion) can influence this. In a rodent model where dimethylhydrazine was administered 2 months after surgery, anastomotic tumours were
R K, Phillips, H T, Cook
openaire   +2 more sources

Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing

Advanced Science, EarlyView.
Recent advances in smart nanotechnologies are expanding the toolbox for brain interfacing, from wireless neuromodulation and high‐resolution sensing to targeted delivery within the central nervous system. By combining responsive nanomaterials with bioinspired design, these platforms enable multimodal interactions with neurons and glia, while also ...
Tommaso Curiale, Marie Celine Lefevre, Alessio Carmignani, Maria Cristina Ceccarelli, Matteo Battaglini, Attilio Marino, Gianni Ciofani   +6 more
wiley   +1 more source

Outside-In-Outside Repair Technique for Anterior Horn and Body Meniscal Tear: A Modified Technique

Arthroscopy Techniques
Meniscus is an important structure within the knee to maintain stability and load gravity distribution. Compared with meniscectomy, timely meniscal repair can reduce the risk of knee regression and laxity.
Guorui Cao, M.D., Xiaotan Shi, M.M., Xiao Wang, M.M., Lanbo Yang, M.D., Honglue Tan, M.D.   +4 more
doaj   +1 more source