Results 51 to 60 of about 2,398,936 (356)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Closed circuit TV system monitors welding operations [PDF]

open access: yes, 1967
TV camera system that has a special vidicon tube with a gradient density filter is used in remote monitoring of TIG welding of stainless steel.
Gilman, M.
core   +1 more source

Selection and experimental evaluation of low-cost porous materials for regenerator applications in thermoacoustic engines [PDF]

open access: yes, 2010
This paper aims at evaluating three selected low-cost porous materials from the point of view of their suitability as regenerator materials in the design of thermoacoustic travelling wave engines.
Abduljalil, Abdulrahman S.   +2 more
core   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Axial Cyclic Testing of Concrete-Filled Steel Tube Columns in Diagrid Structures

open access: yesAdvances in Civil Engineering, 2019
Inclined concrete-filled steel tube (CFST) columns in a diagrid structure system can efficiently carry large vertical loads and horizontal forces. This paper presents an experimental study of the stress characteristics of engineered inclined CFST columns
Qingxuan Shi, Wenzhe Cai, Bin Wang
doaj   +1 more source

Practical Evaluation Method for the Pouring Scheme of a Long-Span Concrete-Filled Steel Tube Arch Bridge

open access: yesAdvances in Civil Engineering, 2022
Concrete pouring steel tube arch is a critical part in the construction of a long-span concrete-filled steel tube arch bridge. With the adoption of the improved TOPSIS, this study summarized five indicators that controlled the concrete-filled steel tube ...
Xinyu Yao, Tianzhi Hao, Nianchun Deng
doaj   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

Shock Theory of a Bubbly Liquid in a Deformable Tube [PDF]

open access: yes, 2010
Shock propagation through a bubbly liquid filled in a deformable cylindrical tube is considered. Quasi-one-dimensional bubbly flow equations that include fluid-structure interaction are formulated, and the steady shock relations are derived ...
Ando, K.   +5 more
core  

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

open access: yesFEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru   +6 more
wiley   +1 more source

Shear bearing capacity calculation of low-rise SFRC shear wall with CFST columns based on simplified softened strut and tie model

open access: yesFrontiers in Materials
In the paper, an innovative shear wall, which is referred to as steel fiber reinforced concrete (SFRC) shear wall with concrete filled steel tube (CFST) columns, is introduced, based on the high bearing capacity and large stiffness of concrete filled ...
Peibo You   +5 more
doaj   +1 more source

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