Results 61 to 70 of about 17,784 (265)
FEBS Open Bio, EarlyView.Drugs previously repurposed to target blood cancers reduced neuroblastoma and glioblastoma cell growth and viability. However, their levels of anticancer activity were different and their clinical application may be problematic due to side effects at effective doses.
Abhishek Kharawatkar +4 more
wiley +1 more source
Fenmo yejin jishuNuclear energy is a kind of clean energy, developing the Gen IV nuclear energy systems with higher safety and economy is the focus in current research. Traditional zirconium alloys have been unable to adapt to the harsh service environment of the Gen IV ...
ZHAI Yazhong +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
Aligning Figurative Paintings With Their Sources for Semantic Interpretation.
International Journal of Interactive Multimedia and Artificial IntelligenceThis paper reports steps in probing the artistic methods of figurative painters through computational algorithms. We explore a comparative method that investigates the relation between the source of a painting, typically a photograph or an earlier ...
Sinem Aslan, Luc Steels
doaj +1 more source
Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins
FEBS Open Bio, EarlyView.Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley +1 more source
24 pages, contribution to the CAS - CERN Accelerator School: Mechanical & Materials Engineering for Particle Accelerators and Detectors, 2-15 June 2024, Sint-Michielsgestel ...
openaire +2 more sources
Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells
FEBS Open Bio, EarlyView.Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim +4 more
wiley +1 more source
Cailiao gongchengLaser additive manufacturing （LAM） enables the integrated direct formation of high-performance metallic components with complex geometry. However， the non-uniform distribution of temperature gradients， in-situ heat treatment effects， non-equilibrium ...
WANG Ruixin +8 more
doaj +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Journal of Materials Research and TechnologyIn this work, we employ a Split Hopkinson Pressure Bar (SHPB) to investigate the microstructural evolution and formation mechanism of internal adiabatic shear bands (ASBs) in a 2000 MPa grade ultrahigh strength martensitic steel at high strain rates ...
Ruizhe Jin +5 more
doaj +1 more source