Results 71 to 80 of about 224,077 (308)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Latest developments in mechanical properties and metallurgical features of high strength line pipe steels [PDF]

open access: yes, 2013
In response to the increasing demand to improve both transportation efficiency and performance, the steel pipe industry has conducted extensive efforts to develop line pipe steel grades with superior metallurgical and mechanical (strength, toughness and ...
Belato Rosado, Diego   +3 more
core   +2 more sources

Review on the prediction of residual stress in welded steel components [PDF]

open access: yes, 2020
Residual stress after welding has negative effects on the service life of welded steel components or structures. This work reviews three most commonly used methods for predicting residual stress, namely, empirical, semi-empirical and process simulation ...
Abdel Wahab, Magd   +2 more
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Aligning Figurative Paintings With Their Sources for Semantic Interpretation.

open access: yesInternational Journal of Interactive Multimedia and Artificial Intelligence
This paper reports steps in probing the artistic methods of figurative painters through computational algorithms. We explore a comparative method that investigates the relation between the source of a painting, typically a photograph or an earlier ...
Sinem Aslan, Luc Steels
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Aging embrittlement at high temperature of 9Cr3W3Co steel and its improvement method

open access: yesCailiao gongcheng, 2019
The main factor that results in aging embrittlement of 9Cr3W3Co steel was investigated through microstructure observation using scanning electron microscopy (SEM). The amount of each precipitates under equilibrium state in 9Cr3W3Co steel with different W
MA Long-teng, LIU Zheng-dong, BAI Yin
doaj   +1 more source

A New Electron Backscatter Diffraction-Based Method to Study the Role of Crystallographic Orientation in Ductile Damage Initiation

open access: yesMetals, 2020
The third generation of advanced high strength steels shows promising properties for automotive applications. The macroscopic mechanical response of this generation can be further improved by a better understanding of failure mechanisms on the ...
Behnam Shakerifard   +2 more
doaj   +1 more source

Effects of aluminum on hydrogen solubility and diffusion in deformed Fe-Mn alloys [PDF]

open access: yes, 2016
We discuss hydrogen diffusion and solubility in aluminum alloyed Fe-Mn alloys. The systems of interest are subjected to tetragonal and isotropic deformations. Based on ab initio modelling, we calculate solution energies, then employ Oriani's theory which
Dang, S.   +4 more
core   +4 more sources

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