Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Comprehensive Analysis of a Tricycle Structure with a Steering System for Improvement of Driving Properties While Cornering. [PDF]
Materials (Basel), 2022 Blatnický M +3 more
europepmc +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Analysis of driving properties of a three-wheeled vehicle with a newly designed steering system
MATEC Web of Conferences, 2019 This paper presents results of analyses of a three-wheeled vehicle with the newly designed steering system. Our design of steering system is intended to be mounted on a tricycle with the electric drivetrain.
Dižo Ján +2 more
doaj +1 more source
Wear Analysis of Materials Used for a Track Steering System in Abrasive Soil Mass. [PDF]
Materials (Basel), 2021 Olejniczak K, Napiórkowski J.
europepmc +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Research on the control and coordination of four-wheel independent driving/steering electric vehicle
Advances in Mechanical Engineering, 2017 A four-wheel-independent-driving and four-wheel-independent-steering control and coordination system is proposed by combining a four-wheel-independent-steering control system and a four-wheel-independent-driving control system. The four-wheel-independent-
Lisheng Jin +5 more
doaj +1 more source
Practicality of electronic beam steering for MST/ST radars, part 6.2A [PDF]
Electronic beam steering is described as complex and expensive. The Sunset implementation of electronic steering is described, and it is demonstrated that such systems are cost effective, versatile, and no more complex than fixed beam alternatives ...
Clark, W. L., Green, J. L.
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Apollo extension system lsv studies. mission command and control [PDF]
Steering system and control circuit for Lunar Surface Vehicle /LSV/ - Apollo ...
Bonham, R. J., Meagher, A. W.
core +1 more source