Results 61 to 70 of about 97,888 (314)

Joint Frequency and DOA Estimation with Automatic Pairing Using the Rayleigh–Ritz Theorem [PDF]

, 2022
This paper presents a novel scheme for joint frequency and direction of arrival (DOA) estimation, that pairs frequencies and DOAs automatically without additional computations.
Du, H, Jia, W, Gao, H
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Performance analysis of beamformers using generalized loading of the covariance matrix in the presence of random steering vector errors [PDF]

, 2005
Robust adaptive beamforming is a key issue in array applications where there exist uncertainties about the steering vector of interest. Diagonal loading is one of the most popular techniques to improve robustness.
Besson, Olivier, Vincent, François
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Steering Acoustic Intensity Estimator Using a Single Acoustic Vector Hydrophone

Journal of Sensors, 2018
Azimuth angle estimation using a single vector hydrophone is a well-known problem in underwater acoustics. In the presence of multiple sources, a conventional complex acoustic intensity estimator (CAIE) cannot distinguish the azimuth angle of each source.
Guangpu Zhang, Ce Zheng, Wang Sheng Lin
openaire   +1 more source

An expected least-squares beamforming approach to signal estimation with steering vector uncertainties [PDF]

IEEE Signal Processing Letters, 2006
We treat the problem of beamforming for signal estimation in the presence of steering vector uncertainties, where the goal is to estimate a signal amplitude from a set of array observations. Conventional beamforming methods typically aim at maximizing the signal-to-interference-plus-noise ratio (SINR).
Yonina C. Eldar, Arye Nehorai, Patricio S. La Rosa   +2 more
openaire   +1 more source

Extended GLRT Detection of Moving Targets for Multichannel SAR Based on Generalized Steering Vector

, 2021
A generalized likelihood ratio test (GLRT) with the constant false alarm rate (CFAR) property was recently developed for adaptive detection of moving targets in focusing synthetic aperture radar (SAR) images.
Chong Song, Bingnan Wang, Wei Li, Maosheng Xiang   +3 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Robust Target Detection and Estimation for Airborne STAP Radar With Arbitrary Array Errors and Target Uncertainty

IEEE Access
In the presence of arbitrary array errors and angle mismatch, performance on target detection and angle estimation will be degraded due to steering vector mismatch.
Jianxin Wu, Yang Zhao, Changxian Li, Peng Shen   +3 more
doaj   +1 more source