Results 131 to 140 of about 10,800 (301)
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
On the embedding capacity of DNA strands under insertion, deletion and substitution mutations
, 2010 Paper presented at Media Forensics and Security XII, SPIE-IS&T Electronic Imaging conference, 18–20 January 2010, San Jose, CaliforniaA number of methods have been proposed over the last decade for embedding information within deoxyribonucleic acid (DNA).
Balado, Félix, Félix Balado
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
A REVIEW ON STEGANOGRAPHY METHODS
, 2020 : In this paper we review different Steganography techniques for hiding the data. Steganography is a technique of hiding the data in any media in such a way that it remains confidential.
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Steganography: Past, Present, Future
, 2001 Steganography (a rough Greek translation of the term Steganography is secret writing) has been used in various forms for 2500 years. It has found use in variously in military, diplomatic, personal and intellectual property applications.
Judge, J C
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
, 2019 Cryptography and Steganography are the two popular methods available to provide security. The former distorts the message and the latter itself hides the existence of the message. Using cryptography, the data is transformed into some other gibberish form
NC DOCKS at Elizabeth City State University +1 more
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Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Comparative Analysis Spread Spectrum and Parity Coding Steganography in E-commerce
The transaction data online has increased compared to the previous communications that mostly in the form of voice and text messaging. To improve the security, data must be protected such a way that it cannot be attacked by unauthorized parties.
Brahim , W +3 more
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source