Results 181 to 190 of about 845 (253)
Our study expands the variant spectrum of PLCZ1, enriches the clinical characteristics of PLCZ1, and provides a solid base for the genetic counseling, diagnosis, and treatment of this condition. ABSTRACT Background Variations in the PLCZ1 gene can lead to male infertility (MIM #617214), an autosomal recessive disorder characterized by failure or ...
Jinwei Yang +12 more
wiley +1 more source
Sifting through the noise: A survey of diffusion probabilistic models and their applications to biomolecules. [PDF]
Norton T, Bhattacharya D.
europepmc +1 more source
City Nuisance Ordinances and Overdose Mortality
ABSTRACT Nuisance ordinances are a class of municipal law that are framed as a way to reduce both police burden and unwanted behaviors such as repeated calls to 911, drug‐related activity, and disorderly conduct. This study explores the effect of nuisance ordinances on drug‐related mortality rates in Ohio and surrounding commuting zones from 1999 to ...
Ashley C. Bradford
wiley +1 more source
On estimates for the ∂¯ equation in Stein manifolds [PDF]
openaire +1 more source
ABSTRACT Understanding the mechanisms through which anti‐cancer treatments influence survival is central to improving drug development and evaluation. In this work, we develop a Bayesian joint modeling framework for mediation analysis to quantify the extent to which tumor size dynamics mediate the effect of treatment on overall survival (OS). Our model
Georgios Kazantzidis +2 more
wiley +1 more source
Covariance Estimation for Wide Data
Covariance matrix estimation is fundamental to multivariate analysis, with applications spanning finance, genomics, climate science, and signal processing. This review synthesizes recent advances in high‐dimensional covariance estimation‐thresholding, linear and nonlinear shrinkage, graphical models, and random matrix theory‐under a unifying framework ...
Eran Raviv
wiley +1 more source
Dimensionality reduction beyond neural subspaces with slice tensor component analysis. [PDF]
Pellegrino A, Stein H, Cayco-Gajic NA.
europepmc +1 more source
Bayesian Full‐Waveform Monitoring of CO2 Storage With Fluid‐Flow Priors via Generative Modeling
Abstract Quantitative monitoring of subsurface changes is essential for ensuring the safety of geological CO2 ${\text{CO}}_{2}$ sequestration. Full‐waveform monitoring (FWM) can resolve these changes at high spatial resolution, but conventional deterministic inversion lacks uncertainty quantification and incorporates only limited prior information ...
Haipeng Li +3 more
wiley +1 more source
Arc Heat Flow and Magmatic Heat Budgets
Abstract We evaluate hydrothermal heat loss from 11 volcanic‐arc segments (∼6,000 km of arc length, ∼10% of the global total), motivated by the observation that much magmatic heat ultimately crosses the land surface as heated aqueous fluid. Heat loss takes place by volcanic eruption, geothermal heat conduction to the surface, fumarolic (vapor ...
S. E. Ingebritsen +7 more
wiley +1 more source
Abstract Since its observation in 2019, the first image of a super‐massive black hole using Very Long Baseline Interferometry (VLBI) with an Earth‐scale baseline has generated much scientific and public interest. Work is now underway to extend the baseline into space to obtain higher image resolution.
E. A. Burt +5 more
wiley +1 more source

