Results 21 to 30 of about 2,486 (97)

Isolated Mast Cell–Mediated Angioedema: Clinically Different but Endotypically Similar to Chronic Spontaneous Urticaria

Clinical &Experimental Allergy, EarlyView.
Thomas Buttgereit, Claudia Hayford, Carolina Vera Ayala, Sherezade Moñino‐Romero, Yi‐Kui Xiang, Pavel Kolkhir, Carolin Steinert, Denise Freier, Markus Magerl, Jörg Scheffel, Karsten Weller   +10 more
wiley   +1 more source

Donor ethnicity, sex, and age impact chondrogenic re‐differentiation capacity: a multi‐demographic study of human articular chondrocytes in vitro

Journal of the Royal Society of New Zealand, Volume 55, Issue 6, Page 1542-1562, December 2025.
ABSTRACT To unravel causes of disparities in osteoarthritis (OA) prevalence and to improve cell‐based cartilage repair treatments, there is need to investigate the multifactorial impact of patient demographics on a biophysiological level. In this study, we systematically analyse single‐ and multi‐demographic impact on in vitro chondrogenic re ...
Laura Veenendaal, Valery Yizhuo Liu, Cameron Lacey, Khoon S. Lim, Gary J. Hooper, Tim B. F. Woodfield, Gabriella C. J. Lindberg   +6 more
wiley   +1 more source

The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies

Obesity Reviews, Volume 26, Issue 12, December 2025.
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin, Stjepan Eržen, Zala Mlinarič, Dubravka Jurišić Eržen, Simon Horvat, Tanja Kunej, Jasna Klen   +6 more
wiley   +1 more source

Versatile Applications of CRISPR‐Based Programmable T‐DNA Integration in Plants

Plant Biotechnology Journal, Volume 23, Issue 12, Page 5950-5964, December 2025.
ABSTRACT Agrobacterium‐mediated T‐DNA integration into plant genomes represents a cornerstone for transgenic expression in plant basic research and synthetic biology. However, random T‐DNA integration can disrupt essential endogenous genes or compromise transgene expression, stressing the need for targeted integration strategies.
Xiao‐Xia Lin, Ben‐Qiang Gong, Feng‐Zhu Wang, Jian‐Bo Wan, Xiangyu Xiong, Jian‐Feng Li   +5 more
wiley   +1 more source

Modeling the Burden of Extreme Weather Events in a Large Network of International HIV Care Cohorts

GeoHealth, Volume 9, Issue 11, November 2025.
Abstract Extreme weather events (EWEs) continue to threaten the health and well‐being of populations across the globe. However, risk from drought and floods is not evenly distributed spatially nor are all populations equally at risk for poor health outcomes.
Sophia D. Arabadjis, Frank Davenport, Ana Maria Vicedo Cabrera, Zachary Shahn, Ellen Brazier, Andrew Maroko, Avantika Srivastava, Gad Murenzi, Timothy John Dizon, Keri N. Althoff, Antoine Jaquet, Aggrey S. Semeere, Yanink Caro Vega, Mark K. U. Pasayan, Sheri D. Weiser, Denis Nash   +15 more
wiley   +1 more source

Rapamycin Does Not Compromise Exercise‐Induced Muscular Adaptations in Female Mice

Aging Cell, Volume 24, Issue 10, October 2025.
Rapamycin is largely compatible with the physical and skeletal muscle benefits of progressive weighted wheel running (PoWeR). The detrimental effects of rapamycin on glucose metabolism in the context of voluntary exercise are mitigated by intermittent dosing.
Christian J. Elliehausen, Szczepan S. Olszewski, Dennis M. Minton, Carolyn G. Shult, Aditya R. Ailiani, Michaela E. Trautman, Reji Babygirija, Dudley W. Lamming, Troy A. Hornberger, Adam R. Konopka   +9 more
wiley   +1 more source

Parental perspectives on family‐centered care in pediatric neurology: An explanatory sequential mixed‐methods study

Developmental Medicine &Child Neurology, Volume 67, Issue 10, Page 1340-1353, October 2025.
The proposed conceptual framework highlighting parents' central role in their child's healthcare experience. This original article is commented by Kettle‐Frisby on pages 1247–1248 of this issue. Abstract Aim To explore parents' experiences of family‐centered care (FCC) in a pediatric neurology clinic. Method In this explanatory sequential mixed‐methods
Ege Sarikaya, Courtney B. Cook, Kathryn A. Selby, Ye Shen, GenCOUNSEL Study, Alison M. Elliott, Jehannine Austin, Bartha Knoppers, Larry D. Lynd, Alivia Dey, Shelin Adam, Nick Bansback, Patricia Birch, Lorne Clarke, Nick Dragojlovic, Jan Friedman, Debby Lambert, Daryl Pullman, Alice Virani, Wyeth Wasserman, Ma’n Zawati, Alison M. Elliott   +21 more
wiley   +1 more source

Campbell Title Registrations to Date—September 2025, and Discontinued Protocols

Campbell Systematic Reviews, Volume 21, Issue 4, December 2025.
wiley   +1 more source

Ruptured mature cystic teratoma with granulomatous inflammation masquerading as pseudomyxoma peritonei. [PDF]

Int Cancer Conf J
Steinert F, Hölzen J, Juratli M, Merten J, Witteler R, Wardelmann E, Pascher A, Eichelmann AK.   +7 more
europepmc   +1 more source

Monocolonization with <i>Bacteroides thetaiotaomicron</i> exerts region-specific effects on Alzheimer's disease-related traits in the murine brain. [PDF]

Microbiol Spectr
Nguyen VTT, König S, Formes H, Al Taleb Z, Steinert F, Bufe B, Eggert S, Stegmüller S, Schermer Y, Richling E, Kins S, Reinhardt C, Endres K.   +12 more
europepmc   +1 more source