Results 141 to 150 of about 64,475 (321)
The Astronomical JournalMetal-poor M subdwarfs are among the oldest stellar populations and carry valuable information about the chemical enrichment history of the Milky Way. The measurements of chemical abundances of these stars therefore provide essential insights into the ...
Neda Hejazi +5 more
doaj +1 more source
The Galactic Disk-Halo Transition – Evidence from Stellar Abundances [PDF]
, 2008 P. E. Nissen, W. J. Schuster
openalex +1 more source
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Atomic Data for Astrophysically Important Spectral Lines of Singly Ionized Nitrogen
The Astrophysical JournalNitrogen lines are widely observed in astrophysical spectra and provide important diagnostics for plasma properties. In this work, we present extended calculations for accurate energy levels, electric dipole radiative transition parameters, and lifetimes
M. C. Li, W. Li
doaj +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
A Data-driven Spectral Model of Main-sequence Stars in Gaia DR3
The Astrophysical JournalPrecise spectroscopic classification of planet hosts is an important tool of exoplanet research at both the population and individual system level.
Isabel Angelo +3 more
doaj +1 more source
Carbon and nitrogen abundances of stellar populations in the globular cluster M 2 [PDF]
, 2012 C. Lardo +3 more
openalex +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source