Results 121 to 130 of about 63,862 (294)

The Galactic Thick Disk Stellar Abundances

open access: yesThe Astronomical Journal, 2000
We present first results from a program to measure the chemical abundances of a large (N>30) sample of thick disk stars with the principal goal of investigating the formation history of the Galactic thick disk. Our analysis confirms previous studies of O and Mg in the thick disk stars which reported enhancements in excess of the thin disk population.
Prochaska, Jason X.   +4 more
openaire   +3 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Stellar Ancestry Unlocked: Chemical and Orbital Clues Link Metal-poor Stars to Globular Clusters and the Galaxy’s Thick Disk

open access: yesThe Astronomical Journal
This study presents a detailed chemical, kinematic, and orbital dynamic analysis of five metal-poor stars in the solar neighborhood: HD 2665, HD 5916, HD 122956, HD 189349, and HD 218857.
Gizay Yolalan   +3 more
doaj   +1 more source

Cosmic abundances: The impact of stellar duplicity

open access: yes, 2004
The mass-transfer scenario links chemical peculiarities with stellar duplicity for an increasing number of stellar classes (classical and dwarf barium stars, subgiant and giant CH stars, S stars without technetium, yellow symbiotic stars, WIRRING stars ...
Jorissen, A., Van Eck, S.
core   +1 more source

Stellar abundances of early-type galaxies [PDF]

open access: yes, 2008
It is currently impossible to determine the abundances of stellar populations star-by-star in dense stellar systems more distant than a few megaparsecs. Therefore, methods to analyse the composite light of stellar systems are required. I review recent progress in determining the abundances and abundance ratios of early-type galaxies.
openaire   +2 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Metal-enriched Pair-instability Supernovae: Effects of Rotation

open access: yesThe Astrophysical Journal
In this paper, we revisit metal-enriched rotating pair-instability supernovae (PISNe) models for metallicities consistent with the Small Magellanic Cloud, the Large Magellanic Cloud (LMC), and 0.1 Z _⊙ .
Hideyuki Umeda, Chris Nagele
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Sun Remains Relatively Refractory Depleted: Elemental Abundances for 17,412 Gaia RVS Solar Analogs and 50 Planet Hosts

open access: yesThe Astrophysical Journal
The element abundances of stars, particularly the refractory elements (e.g., Fe, Si, and Mg), play an important role in connecting stars to their planets. Most Sun-like stars do not have refractory abundance measurements since obtaining a large sample of
Rayna Rampalli   +4 more
doaj   +1 more source

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