Results 111 to 120 of about 250,517 (293)

Chemical Abundances in the Leiptr Stellar Stream [PDF]

open access: yes
Stellar streams are useful probes of the Galactic acceleration field, the gradient of the gravitational potential, and the small-scale substructure of the dark matter halo which make them important structures in the study of galaxy formation.
Atzberger, Kaia
core   +1 more source

Stellar pulsation and the abundance of helium

open access: yesThe Astrophysical Journal, 1978
It has been suggested that the appearance of nonvariable stars within the Cepheid strip could be explained by a range in the helium abundance of Population I stars. In order to study this possibility, spectra were obtained of the main-sequence B stars in the galactic cluster NGC 129, which contains a nonvariable Cepheid-strip star, and M25, which ...
openaire   +1 more source

Blue Supergiants in the Pinwheel Galaxy M101: Comparison with H II Region Chemical Abundances, Spectroscopic Distance, and an Independent Determination of the Hubble Constant

open access: yesThe Astrophysical Journal
We present a quantitative spectroscopic study of 13 blue supergiant stars in the Pinwheel Galaxy M101, based on data obtained with the Low Resolution Imaging Spectrometer available at the Keck I telescope.
Fabio Bresolin   +4 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Boron Abundances in Early B Dwarfs of the Galactic Open Cluster NGC 3293

open access: yesThe Astrophysical Journal
New boron abundances or upper limits have been determined for eight early B stars in the young Galactic open cluster NGC 3293, using UV spectra obtained by the Hubble Space Telescope Cosmic Origins Spectrograph.
Charles R. Proffitt   +6 more
doaj   +1 more source

Barium and europium abundances from the Gaia-ESO Survey using The Cannon

open access: yesAstronomy & Astrophysics
Context. Neutron-capture element abundances encode the time-dependent interplay between slow (s-) and rapid (r-) nucleosynthetic processes and provide critical constraints on Galactic chemical evolution.
Das P. B.   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

High-precision stellar abundances of the elements : methods and applications

open access: yes, 2018
Efficient spectrographs at large telescopes have made it possible to obtain high-resolution spectra of stars with high signal-to-noise ratio and advances in model atmosphere analyses have enabled estimates of high-precision differential abundances of the
Nissen, Poul Erik,, Gustafsson, Bengt,
core   +1 more source

Aeos Is Mixing It Up: The (In)homogeneity of Metal Mixing Following Population III Star Formation

open access: yesThe Astrophysical Journal
Stellar surface abundances are records of the state of the gas from which stars formed and thus trace how individual elements have mixed into the surrounding medium following their ejection from stars.
Jennifer Mead   +9 more
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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