Results 101 to 110 of about 63,862 (294)
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
The Astrophysical JournalThe mixing of material in stellar envelopes critically determines surface elemental abundances. A well-established tension remains between theoretical models and observational data for stars near the main-sequence turn-off.
Fei Guo, Xue-Feng Li, Yan Li
doaj +1 more source
Stellar abundances and nucleosynthesis
, 2016 Stellar abundances are essential parameters for many branches of astronomy. They are also particularly important as tests for theories of nucleosynthesis. Despite the encouraging results from band photometry, detailed spectroscopic analyses are still important in furthering knowledge of physical processes occurring in a variety of stellar objects. This
Ellis, R, Ellis, Richard S.
openaire +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The Astrophysical Journal Supplement SeriesAs the field of exoplanetary astronomy has matured, demand has grown for precise stellar abundances to probe subtle correlations between stellar compositions and planetary demographics.
Emily K. Pass +9 more
doaj +1 more source
Stellar Spectral Signatures in High-Redshift Galaxies [PDF]
, 2013 Stellar emission and absorption lines are routinely observed in galaxies at redshifts up to 5 with spectrographs on 8-10m class telescopes. While the overall spectra are well understood and have been successfully modeled using empirical and theoretical ...
Leitherer, Claus
core
Abundance of Helium in Stellar Atmospheres [PDF]
Highlights of Astronomy, 1971 Helium abundance in stellar atmospheres has been the subject of several recent investigations, essentially induced by progresses in the computation of non-grey model atmospheres (including line blanketing in the far U.V.), by considerable advances in the theory of Stark broadening of helium lines, by non local thermodynamic equilibrium (LTE) work for ...
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Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Elemental ratios in stars vs planets
, 2015 Context. The chemical composition of planets is an important constraint for planet formation and subsequent differentiation. While theoretical studies try to derive the compositions of planets from planet formation models in order to link the composition
Alibert, Yann +4 more
core +1 more source
The abundance of helium and stellar pulsation
Astronomical & Astrophysical Transactions, 1998 Radial gradient of relative amplitude of the light variation FV for galactic classical Cepheids is found. The gradient has different signs for two cases: P > 8d and P < 8d. For P > 8d the gradient is negative. This gradient is caused by gradient of helium content in the primordial clouds, where Cepheids were born.
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