Results 251 to 260 of about 91,576 (294)

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

The faintest, extremely variable X-ray tidal disruption event from a supermassive black hole binary? [PDF]

Innovation (Camb)
Huang M, Xue Y, Li S, Liu F, Zhu S, Chen JH, Shen RF, Wang Y, Yang Y, Jiang N, Bauer FE, Vignali C, Zou F, Wang J, Filippenko AV, Luo B, Qin C, Quirola-Vásquez J, Wang JX, Fan L, Sun M, Wu Q, Ni Q, Brink TG, Wang T, Zheng W, Shu X, Zheng X, Lin X, Kong X, Wang Y, Luo Y, Lin Z.   +32 more
europepmc   +1 more source

Ofatumumab in Myelin Oligodendrocyte Glycoprotein Antibody–Associated Disease: A Comparison With Rituximab

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To evaluate the efficacy and safety of ofatumumab in patients with myelin oligodendrocyte glycoprotein antibody–associated disease (MOGAD), and compare it with rituximab. Methods We conducted a single–center, observational study including 22 MOGAD patients treated with ofatumumab and 21 treated with rituximab.
Yuxin Fan, Lei Zhou, Jingzi ZhangBao, Hongmei Tan, Zhouzhou Wang, Chao Quan   +5 more
wiley   +1 more source

A young gas giant and hidden substructures in a protoplanetary disk. [PDF]

Nat Astron
Ribas Á, Vioque M, Zagaria F, Longarini C, Macías E, Clarke CJ, Pérez S, Carpenter J, Cuello N, de Gregorio-Monsalvo I.   +9 more
europepmc   +1 more source

Dimethyl Fumarate, But Not Rituximab, Reduces Serum GFAP Levels and PIRMA in Relapsing–Remitting MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Serum neurofilament light chain (sNfL) and glial fibrillary acidic protein (sGFAP) levels are believed to reflect mainly acute and chronic disease processes in multiple sclerosis (MS), respectively. In this study, we investigated whether dimethyl fumarate (DMF) and rituximab (RTX) differentially affect these biomarkers.
F. Shawket, J. Lycke, J. Salzer, F. Piehl, K. Fink, N. Lange, J. Mellergård, C. Malmeström, P. Sundström, I. Erngren, A. al‐Grety, E. Freyhult, K. Kultima, J. Burman, A. Svenningsson   +14 more
wiley   +1 more source

Determination of the mass distribution of the first stars from the 21-cm signal. [PDF]

Nat Astron
Gessey-Jones T, Sartorio NS, Bevins HTJ, Fialkov A, Handley WJ, de Lera Acedo E, Mirouh GM, Izzard RG, Barkana R.   +8 more
europepmc   +1 more source

Movement Disorders in Aicardi–Goutières Syndrome and Response to Immunomodulation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This study characterizes movement disorders and treatment responses in seven children with Aicardi–Goutières syndrome (AGS). We retrospectively evaluated motor phenotypes, neuroimaging, and interferon signatures in patients treated with baricitinib or anifrolumab. Spasticity affected all patients, while dystonia was present in 4/7.
Enrique Gonzalez Saez‐Diez, Monica Ferrer Socorro, Kathryn Yang, Nicole Battaglia, Zainab Zaman, Mariko Bennett, Adeline Vanderver, Pui Y. Lee, Lauren A. Henderson, Milena M. Andzelm, Darius Ebrahimi‐Fakhari   +10 more
wiley   +1 more source

Exploring the sub-Neptune frontier with JWST. [PDF]

Proc Natl Acad Sci U S A
Madhusudhan N, Holmberg M, Constantinou S, Cooke GJ.   +3 more
europepmc   +1 more source

Models and observational predictions of dust traps in protoplanetary discs. [PDF]

Astrophys Space Sci
Pinilla P.
europepmc   +1 more source

The emergence of globular clusters and globular-cluster-like dwarfs. [PDF]

Nature
Taylor ED, Read JI, Orkney MDA, Kim SY, Pontzen A, Agertz O, Rey MP, Andersson EP, Collins MLM, Yates RM.   +9 more
europepmc   +1 more source