Results 141 to 150 of about 35,614 (300)

Paracrine Factor Local Gradient‐Generating System for Engineering Perfusable Vascularized Hepatocyte Tissues with Perfusion‐Induced Proliferation

Advanced Healthcare Materials, EarlyView.
A paracrine factor local gradient (PFLG)‐generating system enables microvessel penetration across 3D hepatocyte tissues. The resulting vascularized constructs recapitulate hepatic sinusoidal hepatocyte—endothelial contact architecture and enhance hepatic functions in vitro.
Yen‐Hsiang Huang, Tadahiro Yamashita, Ryo Sudo   +2 more
wiley   +1 more source

Coordinated Space- and Ground-based Monitoring of Accretion Bursts in a Protoplanetary Disk: Establishing Mid-infrared Hydrogen Lines as Accretion Diagnostics for JWST/MIRI

The Astrophysical Journal
In this paper, we establish and calibrate mid-infrared (MIR) hydrogen recombination lines observed with the James Webb Space Telescope as accretion tracers for pre-main-sequence stars that accrete from circumstellar disks.
Benjamin M. Tofflemire, Carlo F. Manara, Andrea Banzatti, Klaus M. Pontoppidan, Joan Najita, Brunella Nisini, Emma T. Whelan, Justyn Campbell-White, Hala Alqubelat, Adam L. Kraus, Christian Rab, Adrien Houge, Sebastiaan Krijt, James Muzerolle, Eleonora Fiorellino, Myriam Benisty, Lukasz Tychoniec, Colette Salyk, Guillaume Bourdarot, Jacob Hyden   +19 more
doaj   +1 more source

Diels‐Alder Click Chemistry as a Dynamic‐Covalent Crosslinking Method in Spheroid‐Encapsulating Hydrogels for Cartilage Engineering

Advanced Healthcare Materials, EarlyView.
This research shows the development of hydrogels with Diels‐Alder click chemistry for engineering cartilage‐like tissue. The hydrogels support cartilage spheroids which could be cultured for at least 28 days. Furthermore, the spheroids showed a tendency to fuse together into a more consistent construct, and produced important components needed for ...
Sanne M. van de Looij, Antonia G. Vasilopoulou, Lennard Spauwen, Antoinette van den Dikkenberg, Jasmijn V. Korpershoek, Mylene de Ruijter, Jos Malda, Bas G. P. van Ravensteijn, Tina Vermonden   +8 more
wiley   +1 more source

Eccentric Binaries Accreting from Thin Disks: Orbital Evolution

The Astrophysical Journal
Circumbinary disks crucially affect the orbital and electromagnetic properties of binary systems across the Universe, from stars in our Galactic neighborhood to supermassive black hole binaries formed as the result of tumultuous galactic mergers ...
Alexander J. Dittmann, Geoffrey Ryan, Luciano Combi   +2 more
doaj   +1 more source

Origins of coplanar counterrotating stellar disk components in late-type galaxies

Astronomy & Astrophysics
Context. Understanding galaxy evolution is key to explaining the structures we observe in the present-day Universe. Counterrotating stellar disks, i.e., co-spatial stellar disks rotating with opposite angular momentum, have been proposed as signatures of
Bugueño M. C., Gómez Facundo A., Dolfi Arianna, Tissera Patricia B.   +3 more
doaj   +1 more source

Gamma-ray bursts from stellar mass accretion disks around black holes

The Astrophysical Journal, 1993
A cosmological model for gamma-ray bursts is explored in which the radiation is produced as a broadly beamed pair fireball along the rotation axis of an accreting black hole. The black hole may be a consequence of neutron star merger or neutron star-black hole merger, but for long complex bursts, it is more likely to come from the collapse of a single ...
openaire   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

Coupled Disk-star Evolution in Galactic Nuclei and the Lifetimes of QPE Sources

The Astrophysical Journal
A modest fraction of the stars in galactic nuclei fed toward the central supermassive black hole (SMBH) approach on low-eccentricity orbits driven by gravitational-wave radiation (extreme mass ratio inspiral (EMRI)).
Itai Linial, Brian D. Metzger
doaj   +1 more source

3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence

Advanced Healthcare Materials, EarlyView.
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes, Timo Rademakers, Ana Filipa Henriques Lourenço, Andrea Calore, Clarissa Tomasina, Denis van Beurden, Jinjie Venema, Bryan Chömpff, Hong Liu, Nicole Bouvy, Sandra Camarero‐Espinosa, Lorenzo Moroni   +11 more
wiley   +1 more source

Thermal Spectra of Warped and Broken Accretion Disks

The Astrophysical Journal
Black holes may accrete gas with angular momentum vectors misaligned with the black hole spin axis. The resulting accretion disks are subject to Lense–Thirring precession, and hence torque. Analytical calculations and simulations show that Lense–Thirring
J. Speicher, O. Blaes
doaj   +1 more source