Results 31 to 40 of about 801 (259)

Alignment of Stellar and AGN Accretion Disks from SDSS Data [PDF]

open access: yesProceedings of the International Astronomical Union, 2009
Lagos, Padilla & Cora (2009) show that if alignments between the galaxy kinematics and the AGN system were to occur, massive galaxies should host BHs with high spin values, regardless of the detailed physics of the BH. Since the BH spin regulates the mass-to-energy conversion (Marconi et al. 2004) and possibly the existence of radio jets (Sikora et
Claudia del P. Lagos   +3 more
openaire   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Secret of Longevity: Protoplanetary Disks as a Source of Gas in Debris Disks

open access: yesThe Astrophysical Journal
While protoplanetary disks (PPDs) are generally thought to disperse within several million years, recent observations have revealed gas in their older counterparts, debris disks.
Wataru Ooyama   +4 more
doaj   +1 more source

Accretion Disks in the Sub-Stellar Realm: Properties and Evolution [PDF]

open access: yesProceedings of the International Astronomical Union, 2009
AbstractIt is now well established that young brown dwarfs harbor accretion disks –and thus undergo a T Tauri phase– similar to their low-mass stellar counterparts. The supporting evidence includes infrared and millimeter observations of the dust component as well as optical and infrared spectra with signatures of gas accretion and outflow.
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Evolution of the Accretion Rate of Young Intermediate-mass Stars: Implications for Disk Evolution and Planet Formation

open access: yesThe Astronomical Journal
This work presents a study of the evolution of the stellar accretion rates of pre-main-sequence intermediate-mass stars. We compare the accretion rate of the younger intermediate-mass T Tauri stars (IMTTSs) with the older Herbig stars into which they ...
Sean D. Brittain   +3 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Planet Formation Regulated by Galactic-scale Interstellar Turbulence

open access: yesThe Astrophysical Journal Letters
Planet formation occurs over a few Myr within protoplanetary disks of dust and gas, which are often assumed to evolve in isolation. However, extended gaseous structures have been uncovered around many protoplanetary disks, suggestive of late-stage infall
Andrew J. Winter   +2 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

open access: yesFEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

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