Results 91 to 100 of about 95,404 (302)

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Initial Mass Functions of Young Stellar Clusters from the Gemini Spectroscopic Survey of Nearby Galaxies. I. Young Massive Clusters in the Antennae Galaxies

open access: yesThe Astronomical Journal
The stellar initial mass function (IMF) is a key parameter to understand the star formation process and the integrated properties of stellar populations in remote galaxies.
Jae-Rim Koo, Hyun-Jeong Kim, Beomdu Lim
doaj   +1 more source

Evidence for Cosmic Acceleration Is Robust to Observed Correlations between Type Ia Supernova Luminosity and Stellar Age [PDF]

open access: bronze, 2020
Benjamin Rose   +8 more
openalex   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

open access: yesMolecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti   +10 more
wiley   +1 more source

zoomies: A Tool to Infer Stellar Age from Vertical Action in Gaia Data

open access: yesThe Astrophysical Journal
Stellar age measurements are fundamental to understanding a wide range of astronomical processes, including Galactic dynamics, stellar evolution, and planetary system formation. However, extracting age information from main-sequence stars is complicated,
Sheila Sagear   +5 more
doaj   +1 more source

The stellar populations of the bluest low surface brightness galaxies

open access: yes, 2005
Using optical/near-IR broadband photometry together with Halpha emission line data, we attempt to constrain the star formation histories, ages, total stellar masses and stellar mass-to-light ratios for a sample of extremely blue low surface brightness ...
Beijersbergen   +65 more
core   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

JADES + JEMS: A Detailed Look at the Buildup of Central Stellar Cores and Suppression of Star Formation in Galaxies at Redshifts 3 < z < 4.5

open access: yesThe Astrophysical Journal
We present a spatially resolved study of stellar populations in six galaxies with stellar masses M _* ∼ 10 ^10 M _☉ at z ∼ 3.7 using 14-filter James Webb Space Telescope (JWST)/NIRCam imaging from the JADES and JEMS surveys. The six galaxies are visually
Zhiyuan Ji   +32 more
doaj   +1 more source

Old-Aged Stellar Population Distance Indicators [PDF]

open access: green, 2018
Rachael L. Beaton   +10 more
openalex   +1 more source

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