Results 161 to 170 of about 8,281,459 (308)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

THE PANCHROMATIC HUBBLE ANDROMEDA TREASURY. III. MEASURING AGES AND MASSES OF PARTIALLY RESOLVED STELLAR CLUSTERS [PDF]

, 2012
Lori C. Beerman, L. Clifton Johnson, M. Fouesneau, Julianne J. Dalcanton, Daniel R. Weisz, Anil C. Seth, Ben Williams, Eric F. Bell, L. Bianchi, Nelson Caldwell, Andrew E. Dolphin, Dimitrios A. Gouliermis, Jason S. Kalirai, S. S. Larsen, Jason Melbourne, Hans‐Walter Rix, Evan D. Skillman   +16 more
openalex   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

Molecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece, Giulio Lovato, Ilaria Cela, Arianna Mercatelli, Benedetta Ferro, Jussi Nikkola, Sara Pagotto, Tommaso Grottola, Vincenzo De Laurenzi, Rossella Cicchetti, Antonio Marchetti, Luigi Schips, Rossano Lattanzio, Stefano Iacobelli, Emily Capone, Peter Black, Mads Daugaard, Michele Marchioni, Gianluca Sala   +18 more
wiley   +1 more source

Using a neural network approach and starspots dependent models to predict effective temperatures and ages of young stars. [PDF]

PLoS One
Tarantino M, Prisinzano L, D'Angelo N, Damiani F, Adelfio G.   +4 more
europepmc   +1 more source

The Gaia-ESO Survey: open clusters in Gaia-DR1 A way forward to stellar age calibration

, 2018
S. Randich, E. Tognelli, R. J. Jackson, R. D. Jeffries, S. Degl’Innocenti, E. Pancino, P. Re Fiorentin, A. Spagna, G. G. Sacco, A. Bragaglia, L. Magrini, P. G. Prada Moroni, E. J. Alfaro, E. Franciosini, L. Morbidelli, V. Roccatagliata, H. Bouy, Luca Bravi, F. Jiménez-Esteban, C. Jordi, Eleonora Zari, G. Tautvaišienė, A. Drazdauskas, Š. Mikolaitis, G. Gilmore, S. Feltzing, A. Vallenari, T. Bensby, S. E. Koposov, A. J. Korn, A. C. Lanzafame, R. Smiljanić, A. Bayo, G. Carraro, M. T. Costado, U. Heiter, A. Hourihane, P. Jofré, J. Lewis, L. Monaco, L. Prisinzano, L. Sbordone, S. G. Sousa, C. C. Worley, S. Zaggia   +44 more
openalex   +2 more sources

AN AGE CONSTRAINT FOR THE VERY LOW MASS STELLAR/BROWN DWARF BINARY 2MASS J03202839–0446358AB [PDF]

, 2009
Adam J. Burgasser, Cullen H. Blake
openalex   +1 more source

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

On the coincidence between the close passage of HD7977 and the Pliocene-Pleistocene transition. [PDF]

Sci Rep
Cao Z, Loeb A, MacLeod M.
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source